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Does Wellbutrin cause weight gain or loss?

I am taking Wellbutrin and i wanted to know if it causes weight loss or gain. Also will it interact with my Lipo& B12 shots... please respond.
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Avatar universal
This did the same for my brother when he was taking it to try quit chewing and it did change his sex drive and weight. But as for me I have never really seen a huge change in sex or weight. Maintained my weight. But, I had to go off it for a year due to a type 1 med. and just started back on it so hopefully being older it can help reduce my weight that I did gain which is only 10 lbs. but at my age of 47 its definitely tougher.  Good luck to us all struggling with depression or more.
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Avatar universal
I was on Wellbutrin XL for 5 yrs. and I feel that it worked very well for me. My family has depression and I have found that I'm also a SAD which is seasonal depression to make it worse. The winter's are very hard for me. I don't like the cold or snow. I had to go off it a year ago when I was put on metformin for type 1 but my scores are normal now but was but on Zoloft for the depression part and my brain was in a fog all the time and angry bouts all the time didn't matter what was going on so I'm going back on Wellbutrin as of tomorrow. I didnt have a huge weight loss with it and for 5'4 and 165 lbs. this is the most I have ever weighed. I'm 47 and the doctor just says its the change in life. Really have heard that since my hyderectomy when I was 30. But, I do feel that it is a safe drug with less side effects than most. So, it was my choice to request it back with the winter depression that I struggle with so much and I do feel happier and able to control my anger with life situations better and no brain fog. Best of luck to all.
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I have gained about 15 lbs. on the generic 150 and have had mood changes, depression, extreme hunger, suicidal thoughts, I haven't changed my food intake before I gained the weight, I am taking more fruit and veggies and exercising and not able to lose.
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Avatar universal
Me too !  Tired of being sad and stressed.
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I've battled fatigue and low moods for as long as I can remember...Doctor said I was pre-diabetic gave me Metphormin (made me horribly ill) so I only took it for 1 week along with phentermine (for weightloss) only taking 1/2 pill daily which it did not help me loose any weight so I stopped it as well and my recent check up I complain of no energy and occassional sugar cravings and he insists Wellbutrin will be the answer which I was leary of because of past all bad experiences with any type of anti-depressants but I wanted to be fair to him and at least give it a try.  I'm on my third day of 1 dose of bupropion SR 140 mg tablet (purple) and I do not feel well at all.  Stomach cramps similar to diarreha but nothing comes out and slight headache and very very sleepy and sluggish.  Is this normal?  Will this pass?  I'm about ready to give up and I'm supposed to be taking 2 doses per day for a total of 300 mg but I'm afraid to take the second dose if the 1 dose is making me feel this bad.  Any input is much appreciated as I'm desperate for relief for my extreme fatigue and inability to loose weight but not if I have to go from feelin bad to worse....please help..anyone....
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Avatar universal
Are you taking Wellbutrin SR or Wellbutrin XL
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Arlington, VA
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