My docotor is leaning towards Alimta at this point because its very tolerable. I was just wondering since my responses to Taxol in the past was the most effective in reducing my markers would taxotere make more sense. Or is my logic not that good. as we all know cancer is rarely logical. Since I have had Avastin for the past 18 months, last last 6 with Nexavar would an oral cytoxin in place of the nexavar provide any positives or have I run the course on Avastin at this point
thank you so much - Judy
Hi Judy,
You seem to have a sensitive tumor, with a good anatomical control seven years after stage 4 disease. This gives makes me optimistic that in future too, you should continue to do well.
You have received carboplatin, Taxol (paclitaxel), Doxil (liposomal doxorubicin), Gemzar (gemcitabine), Abraxane (nab paclitaxel), Avastin (bevacizumab), and Nexavar (Sorafenib).
There are still many effective drugs that may be useful in your case (That is the beauty of the ovarian ca biology - in many women, it continues to be sensitive to many lines of chemotherapy even in advanced disease). According to the National Comprehensive Cancer Network (nccn.org), the effective drugs (apart from the ones you have already had) include cisplatin, Taxotere (docetaxel), etoposide, Alimta (pemetrexed), and topotecan. Several other potentially active agents are available.
In your case, single agent cisplatin, single agent Taxotere, or a combination of these two agents may be reasonable options at this time. You may like to keep other options for future use.
Please feel free to ask follow-up questions.
All the best, and God Bless!