Why can't I take Savella and Pristiq together?

[ivybreeze1960]

I have fibromyalgia, degenerative arthritis and yes, clinical depression.  When I take Savella and Pristiq together, it works wonders.  When both my pain dr and my psychiatrist got together and said I couldn't take them together, I became very depressed after getting off of Savella.  I didn't want to kill myself, but I sure didn't want to live.  Lyrica put me to sleep in horrible ways, Cymbalta doesn't work for me and anything like Prozac or Lexapro or Zoloft is candy to me.  I also take Norco.  But I WANT to take Savella and Pristiq together because FOR ME it works...why do they say I can't????  I am calling my psychiatrist today, cause I cannot take this feeling anymore.  I've taken pretty much everything.  I've not taken mobic, I have a friend that says it is good, but she doesn't have depression.  I also hold down a full time job.  Thank you and you all have a blessed day.

[bargainteach10]

I DO take Pristiq and Savella together and have been doing so for 2 1/2 years now.  My new doctor said they were the same thing and that I should drop Pristiq, which I did for a while with awful results.  I went back to the doctor and explained what had been happening since I went off of it.  He immediately put me back on it and said that since it was working for me, he could find no research that said that it should not be done, just that it normally wasn't.  He said that MOST people did not need that much of this type of medicine, but a few people did and I apparently was one of them.  I have stayed on it since that time and have made it fine.  

Let me know if you ever hear anything contrary to what I have said about it being okay to take both of them together.  I trusted my doctor, who has since passed away, but my new doctor hasn't remarked about this yet (I have only seen her one time), but she might at a later time.  Hope I helped answer your question in some small way.

[Magnakasha]

I'm on both now too.  How much of each are you taking?

[AquaEyesVa]

I was on both as well and my psychiatrist took me OFF the Pristiq bc she said both drugs were Serotonin uptake inhibitors, I think??  She said that could have been why I was so very anxious all of the time.  BUT, since being off of the Pristiq, I have become very, very depressed,  socially alienated, hopeless, I have lost my zest for living, even in light of the birth of my first grandbaby.  I go back to my doctor on Wednesday and pray to God that she has an answer.  I feel like I'm drowning!!!

[sara12345]

What did your doctor tell you?

[shebas2]

I was on both Pristiiq 100mg. And Savella 50mg daily but my doctor told me I couldn’t do that. So he changed me to Pristiq 100mg twice daily. I have been so depressed!!  We know our bodies!!  I like me and who I am, and how I feel on the Prisriq/Savella combo much better!!!  Doctors listen please!!!

[GuitarRox]

The reason why you can't do it is that Prestiq and Savella are in the same class of medications. They do the same things. If your medication isn't working and you continue to be depressed, please talk to your doctor. They can tweak prestiq further, change completely to savella or change all together. That they are both the same thing, an SNRI means that you don't need both, just one at the right dose.