Hi! I am a 44 year old female who is struggling....for nearly a year now I have struggled with sickness. I've had the flu (yes I had the flu vaccine), pneumonia, pleurisy, several respiratory infections, potassium has dropped too low, chest pain, shortness of breath, headaches, lots and lots of joint pain and tingling in feet and hands, extremely cold feet and hands, lots of swelling and extreme fatigue. After 2 hospital visits, a stress test, and several other tests my Primary Physician ran a huge series of blood tests. My first ANA panel came back positive for ANA Titer 1, 1:160 with a Centromere Pattern, nothing else came back positive....all symptoms still there and getting worse, now I've added night sweats and stomach cramps (that would wake me up in the night) and lots of hand, leg and feet cramps. She referred me to a rheumatologist and she ran the tests again. This time, my ANA positive jumped to 1:1640 and I still have the Centromere Pattern but nothing else is coming back positive. I still have all the symptoms listed above and some days it is worse. My hands are weak, hurt a lot, swell all the time. I am now on Plaquenil, 200 mg twice a day, which from what I gather from the rheumatologist is a basic autoimmune medication. She has thrown out words like Lupus, Scleroderma, Raynauds and she said until others become positive we don't really know what we are dealing with. Can anyone shed any light, hope of a diagnosis, guidance? Thank you so much for any words you can share.