About 5 weeks ago we bought my son a new bed off Craigslist. We decided to use my daughters mattress for his bed and get my daughter a new one. The first couple days my son slept in the bed he noticed a little bit of red bumps on his back ( mostly shoulder blades) After a week of sleeping in the new bed he had hives on his face, neck chest, back arms . Terribly itchy. We thought he might have chicken pox and took him to urgent care. They said, no, just hives. Give Benedryl (duh??) and hydro cortisone. Thankful it wasn't chicken pox we went home. the next evening he was twice as bad, going crazy with itching, so we took him to his primary doctor who prescribed prednisone, and a stronger analgesic. It helped!, But not all the way. We suspected the bed because it is the only thing new in our home. No new soaps, fabrics. etc... So my son stopped sleeping in the bed. finally a week or two after not sleeping in the bed he is well. We tested this with my other daughter and she slept in the bed for two nights, and got a few hives, so she stopped. A week later she broke out terribly all over her arms, face, neck and torso. A couple days later she is better. So the question is could it be the wood bed frame? If so, how? It is not touching their bodies. If it is the mattress, why didn't it bother my daughter before? Desperately seeking answers...