Hello and thank you for your question. Very sorry for your husband's diagnosis. Has he sine met with an oncologist to discuss the findings of his testing results? Please give us an update and we'll discuss further. Metastatic deposit of melanoma means that it actually originates from somewhere else. I'm sure that is an issue of concern. Again, please update us. Staging of melanoma is complex. https://www.cancer.org/cancer/melanoma-skin-cancer/detection-diagnosis-staging/melanoma-skin-cancer-stages.html This link goes through staging. However, to be stage 4, distant lymph nodes and/or organs such as liver, lungs or brain are affected. Please let us know how things are going.