Aa
Aa
A
A
A
Close
Avatar universal

Does Effexor XR really work for anybody???

I have read many, many posts about Effexor XR and the hellish experience people have on this medication.  My doctor just put me on it after several months of so-so performance by Lexapro.  Here is the question...is there anybody out there, any one, who would say "Effexor XR is awesome, it has been a great medication and I am grateful to be on it?"  If so, I would love to hear what you have to say, what your experience has been, dosage, etc.  My script has been for GAD/depression.  I have been in therapy (cognitive with a psychologist) since June.  Some progress, but the feelings still remain.  I am trying to find some way to turn the volume down on emotions.  I take Lorazepam (Ativan) - 1mg - occassionally when anxiety is unbearable.  I take Ambien CR to sleep.  So...any cocktail stories out there?
67 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Usual dose for Seroquel is 300mg once at bedtime. It will knock you out so don't take it in the morning. A very usual combination with Seroquel is Lamictal. I take 200mg once in the morning.

After still spending too mush time being depressed, I began a drug in combination with these two called Emsam. I was stuck in depression for years and within days I was feeling energetic and hopeful again. Changed my life.

Last, if you are seeing an MD for mental health issues, stop and find a well recommended Psychiatrist who can give you an accurate diagnosis. I am my own advocate for my health and after years of researching my condition, my doctor started asking me for my advice and treatments I was receiving. Biggest problem I see is a mental health issue being tackled buy an unknowledgeable MD.

Helpful - 0
Avatar universal
I've been on Effexor now for six months after going to detox and rehab for a 13 year benzo withdrawal (Ativan)  I have seen some improvements but the last month my severe anxiety and depression came back.  My doctor upped my Effexor yesterday to150 and the anxiety and depression are soooooo bad today.  How long until you saw a great improvement?  I am in therapy and will continue.  The pharmacist told me today an increase in anxiety and depression could last up to 2 weeks.  I would appreciate any feedback
Thank you so much!!
Helpful - 0
Avatar universal
It sounds like you could really use some therapy to cope with your feelings.  Also you may need to be on a different anti-depressant.  Hope you feel better.
Sara
Helpful - 0
Avatar universal
I am on slow release venlafaxine. Started on it about four years ago.
Previous to this, in my teens, I was on Prozac for a chemical imbalance.
Had an eight year gap, without any meds. career was good. Family life was good.

then my world caved in; broken marriage, estranged sons, diagnosed with m.e. Cfs, second relationship fell apart. Dose went up.
My Partner was then killed and my life since has been bleak.
My kids that live with me keep me alive, they are my life.
Dose is upto 375mg now, I feel I have been kidding myself and all around me that I manage ok. I find it difficult to just be myself, like I have to seem ok to to other people. On the inside I feel: useless, I get up to sit down, to rest,  I have no energy, my mobility is rubbish, I've put on so much weight my clothes don't fit, my memory and concentration is utter pants. I can't look after myself let alone my home and children. I have Carers to run my home and look after myself and the children. It feels that I'm no use. I keep thinking of myself old and alone. I am not good with crowds. I am a hermit, only going out for appointments. I love my kids dearly but I feel useless. I can't play tractors on the floor or run around playing ball. My world is like sleep and awake, nothing in between. I am in massive debt of over 30k I will never clear in my lifetime that my ex husband left me with. I don't have a life. I am so fearful I will be alone forever, I am fearful of going outside. I want to meet people, but I don't like being in that sort of situation. I feel I can't trust people. I feel paranoid that people talk about me. I feel safe inside my home. But I am so lonely and afraid .... My mum is very poorly now. It's just one thing after another. I need a bit of life in my life. I hurt and ache constantly, with variable severe pain. I'm tired in day but can't always nod off on night. I have a multitude of symptoms I have suffered from since having m.e. I know that's that for me, so I try and interact with my kids, but they know mum is disabled and struggles everyday. Everyday brings difficult challenges for me. but my children keep me alive. I have a support worker etc, but she is not a friend, it's her job. I'm lost
Helpful - 0
Avatar universal
I have to say that Effexor has been a huge life changer for me and I have only been on it for a short period of time. Back in December I was put on my first med, which was Cipralex. I had such a bad reaction to that – it made me suicidal, kept me up more at night (when I was already only sleeping 2-3 hours for two months) and made me incredibly agitated/irritated within a very short period of time so I was taken off of it. I was put on Seroquel/Quetiapine which has helped stabilize my mood and other issues with a benefit of helping me sleep at night (still on it – now on 200mg), but it was not doing anything for my low mood so my psychiatrist decided to try Zoloft which did the exact same thing as Cipralex – and even at such a low dose of 45 mg worked against the sedating effect of Seroquel. Now that I have started Effexor I can actually say that I feel happy and has made me much more productive. It may not be for other people but it is honestly so amazing for me. I have had no side effects at all and it has actually stabilized my hunger (which increased when I started Seroquel). I also have to say that if there are no changes or your anxiety/suicidal ideation that you should really talk to your doctor about going to a different med and if he/she is telling you to wait it out that you need to get a second opinion – my gp (who originally put me on Seroquel) told me that I wasn’t on it long enough to see the good effects – but after my experience going on this drug I completely don’t agree.
Helpful - 0
Avatar universal
I was taking this drug for about two years my pcp said I had to be on Effexor or Prozac or one of their buddies or I would not be able to be able to get my meds for anxiety like lorazepam ? I never really felt depressed but do suffer from anxiety. I have been off all the Prozac and Effexor style drugs and feel alive again. And treat my anxiety with buspar and have never felt better.
Helpful - 0
Have an Answer?

You are reading content posted in the Depression Community

Top Mood Disorders Answerers
Avatar universal
Arlington, VA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
15 signs that it’s more than just the blues
Discover the common symptoms of and treatment options for depression.
We've got five strategies to foster happiness in your everyday life.
Don’t let the winter chill send your smile into deep hibernation. Try these 10 mood-boosting tips to get your happy back
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.