Hello, I had the long lasting bubble for 12 weeks when I had my vitrectomy for RD repair. Yes, it would sometimes break up into a few different sized bubbles one day, the next it would be one again. Pretty annoying isn't it? Towards the end of the twelve days I had a tiny one that suddenly disappeared. I don't think its any concern, but as always, contact your Dr. with any questions - that's what they are there for and they expect it. Regards, Jim