Tired & unwell

[ajsmith72]

My daughter (13 years old) has been feeling tired and sick for approx two weeks.  She has huge headaches, extremely tired and generally feeling unwell.  I took her to doctor who did a blood test all clear apart from it showed she has large red blood cells.  Her B12 was within normal limits and iron good.  Doctor said most likely stomach bug but another week later still no improvement.  All she does is sleep, should we be concerned and any recommendations on what we should do next?

[iris986]

Have they tested her for mononucleosis

[Justcurious2022]

My freshman year of high school i caught mononucleosis (mono) from a friend sharing drinks and other things. My symptoms were like the Flu was how my doctor described it. I was always tired and many aches including bad headaches. After a while I had the chills and a slight fever with a sore throat along with the other symptoms.. If your daughter went to the doctor and the doctor did not say anything about it i would go back and ask. My doctor to told me he could not find anything wrong with me until I was informed my friend in fact had mono I then went back and my doctor then told me that was the cause of my problem

[Red_Star]

Enlarged blood cells (macrocytosis) is shown up on a lab test with elevated MCV (mean cell volume).  Optimum MCV values 87 to 92 cu. microns.  A vitamin B12 serum range under 550pg/mL (405pmol/L) would be a confirmed vitamin B12 deficiency in Japan and most countries in Europe.

The MCV is increased in:

Hereditary anaemia/s

Megaloblastic anaemias (pernicious, folic acid deficiency, B12 deficiency)

Reticulocytosis (acute blood loss response)

Artifact (aplasia, myelofibrosis, hyperglycemia, cold agglutinins)

Liver disease

Hypothyroidism

Drugs (anti-convulsants/zidovidune treatment)