My symptoms of untreated adrenal insufficiency resulted in extreme drugged like sleep for 15/16 hours a day for a month. When in bed I could barely move and was able to slur out a few words at best. Also, worsening of numbness and extreme dizziness were other symptoms.
"The reaction varies with degrees of adrenal insufficiency. Symptoms may include: a sudden feeling of exhaustion, nausea, headache, inability to concentrate, trembling, muscle weakness, loss of peripheral circulation leading to numbness, lack of muscle control, giddiness, slurred speech, and cognitive impairment."
I too had reactions to thyroxine myself. I had very bad adrenal issues, sensitivity to T4 (hyperthyroid for the first week), followed by a month of worsening hypothyroid symptoms.
Causes of not reacting well to thyroxine include:
* Reaction to the fillers and binders.
* Sensitive to T4 - initial T4 dose produces hyperthyroid symptoms (smaller starting doses are required with smaller and slower increases).
* Hypoadrenalism (poor adrenal function) - other terms include adrenal fatigue, adrenal insufficiency, adrenal dysfunction, hypoadrenia.
* Very low ferritin (iron storage) can cause negative reaction like palpitations, nervousness, and anxiety when starting thyroid hormone replacement.
* Natural production of thyroid hormone slows down in response to medication and hypothyroid symptoms worsens. It takes about 4 to 6 weeks for thyroxine to build up in the blood.
I have had night sweats off and on, and I've had a touch of what I assume is allergies for a while, but it is mild enough that I haven't even bothered to touch OTC medications for it besides Aleve for the sinus headaches I wake up with at times.
The only thing that makes me question the nail damage possibility is that they are on three different nails all dispersed separately from each other.
Thanks for the help, and when I see my doctor on the 8th of November I will make sure to update you all on the answers I receive!
Hi there,
I had Infective Endocarditis (SBE) in 2007 and 2008 I had my 1st OHS to repair mitral valve. SBE is a very serious disease and I can assure you that splinter hemms under the nails are the last symptom. With SBE you have severe night sweats, high fevers and mine was only treated and diagnosed 3 months after I had some flue-like symptoms.
It is good that you are going for a complete medical check-up, but normally the splinters are from nail damage and non-specific to any serious illness.
All the best and please do keep us informed on your progress and results.
It can be caused by thyroid conditions as well? That would actually make a lot of sense for me. Both parents and several relatives have thyroid trouble and I've had some bloodwork come back with low levels, but I reacted poorly to even very low doses of synthoid, so I'm not being treated for it at the moment.
Anyway, thank you for the information! I did call my doctor and move the appointment to an earlier time just to get everything cleared up. After typing out my question, I realized that I'm worried enough about this that putting off addressing it is a really ridiculous idea.
I have splinter haemorrages due to too much thyroid hormone. In my case that is due to hyperthyroid flare ups due to Hashimoto's thyroiditis (most common cause of hypothyroidism), once due to a two month very bad Hashitoxicosis flare due to TRAb/TSI antibody seen with Graves disease (splinter haemorrages were bright red during this time), and overmedicating on thyroxine.
My hyperthyroid flare ups can be so mild that the only sign of a bit too much thyroid hormone in the blood is splinter haemorrages and usually my face turns red after having a shower as well. I'm always tired so that symptom doesn't count. LOL
The following list of causes is from "A text atlas of nail disorders" third edition, along with a few additional causes from fpnotebook and gpnotebook.
Reasons for splinter haemorrhages include:
Amyloidosis
Antiphospholipid syndrome
Arterial emboli
Arthritis (notably rheumatoid arthritis and rheumatic fever)
Behçet's syndrome
Blood dyscrasias (severe anaemia, high-altitude purpura)
Buerger's disease
Cirrhosis
Collagen vascular disease
Cryoglobulinaemia (with purpura)
Darier's disease
Dermatomyositis
Drug reactions (especially tetracyclines)
Eczema
Haemochromatosis
Haemodialysis and peritoneal dialysis
Haematological malignancy
Heart disease (notably uncomplicated mitral stenosis and subacute bacterial endocarditis)
High-altitude living
Histiocytosis X
Hypertension
Hypoparathyroidism
Idiopathic (probably traumatic) - up to 20% of normal population
Indwelling brachial artery cannula
Malignant neoplasia
Occupational hazards
Onychomatricoma
Onychomycosis
Oral contraceptives
Palmoplantar keratoderma
Peptic ulcer
Pityriasis rubra pilaris
Polyarteritis nodosa
Psoriasis
Pregnancy
Pterygium
Pulmonary disease
Radial artery puncture
Raynaud's phenomenon
Renal disease
Sarcoidosis
Scurvy
Septicaemia
Severe illness
Systemic lupus erythematosus (SLE)
Scleroderma
Thyrotoxicosis
Minor and repeated trauma
Trichinosis
Vasculitis