Yep. I have those horrid PVCs. Been through it all...for years. You know what stops mine? And its free with no side effects? WATER!! As soon as I feel one, or the start of one or 100, I guzzle half of a 12 to 16 oz. water bottle, Sometimes more but never a whole bottle. Too much water over a short period of time is NOT good. It has done wonders for me! I always have bottled water with me. Try it!! Please let me know if it works for you too! It must have something to do with the guzzeling and holding your breath while you guzzle, but it works for me! I hope it works for you too =)