Most, probably 70% or so, come from the Right Ventricular Outflow Tract.
About 10%-15% come from the Left Ventricular Outflow tract.
The remaining 15%-20% come from all other locations in the Right and Left. Dozens of options there in terms of localization.
So by far Right Sided PVC are most common
Classification of PVC-
Generally you can classify PVC’s in several ways; personally the “scheme” I tend to use to help categorize them goes something like this:
1. Right Sided vs Left Sided-
This determines how easy a PVC is to treat. Left Sided PVCs are less easy to treat and carry higher risk of complications in a procedure in general. (Sorry).
Fortunately a left sided PVC is not automatically more dangerous than a right sided one. Just more difficult to fix!
2. Outflow Tract vs Non Outflow tract
As discussed 80%-85% of PVCS in humans generally are outflow tract PVC’s
15% - 20% are non outflow tract.
Non- Outflow tract have a higher chance of being “malignant” or dangerous in some way. However again, this is not a rule that is written in stone.
However even if a Non-Outflow tract PVC is deemed “Benign” it may warrant a little closer follow up or investigation than an outflow tract PVC. The exception being RVOT PVC in young people, which should be followed a bit further into adulthood to rule out ARVC.
3. Benign vs Malignant
Some PVCs are dangerous (Malignant) others are not (Benign). Among dangerous PVC’s there are generally 3 types.
PVC’s associated with scar tissue (due to heart failure or prior heart attacks), PVC’s associated with Genetic Diseases of the Heart and “High Burden” PVC’s (PVC in excess of 25% of your heartbeats in any given day).