I was diagnosed with intermediate uveitis related to sarcoid and scans showed granulomas in the lungs in 2016. The diagnosis was sarcoid and I was placed on cellcept. Subsequently it was detected that I had developed frequent PVC's - greater than 40,000 per day recorded on holter monitor. After efforts with beta blockers including flecainide and no reduction (MRI and PET CT that could not confirm cardiac sarcoid)_ I had an ablation. (PVC's were at 50% by then) PVC's reduced to almost zero but within 6 months were back up to 10%. In the meantime I moved and had to establish new physicians. (all specialist doctors were and are at medical school centers) The new EP (also a sarcoid expert) believed it was sarcoid and placed recorder for heart. After reviewing results for several months, recommended placing on sotolol and implantation of defibrillator/pacemaker to reduce risk of cardiac arrest because of nonsustained VT. This was done in Feb 2019. Complications occurred - (wire perforation causing pericardial effusion and cardiac tamponade). Recovery has been slow but PVC's have also increased again and are approaching 30%. Because of risk of heart muscle weakening over time with such high levels of PVC's, it is recommended that I consider increasing sotolol or consider another ablation. Since wire penetration is also a risk with ablation - I am somewhat nervous about another procedure. The doctor is not confident that the sotolol will reduce the PVC's. I am aware somewhat of the PVC's but it does not send me to the ER, the shortness of breadth that seems to occur and elevations and stairs becoming more difficult is the biggest side effect. I do walk a fair amount but have not recovered to level before defibrillator implantation.