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My lymphocytes and hbv

I've made some lymphocytes tests, any comments in the context of hbv appreciated:

Leukocytes 6,07 ×103/μl [4,40 - 11,30]
% lymph 43,3 % [21,8 - 53,1]
Lymphocytes 2628 cell/μl
% CD3+ (lymph T) 76,7 % [59,7 - 82,0]
CD3+ (lymph T) 2016 cell/μl [900 - 2600]
% CD3+CD4+ (helper lymph) 52,4 % [30,4 — 51,2] H
CD3+CD4+ (helper lymph) 1378 cell/μl [500 - 1600]
% CD3+CD8+ (cytotoxic lymph) 22,4 % [19,0 - 38,9]
CD3+CD8+ (cytotoxic lymph) 589 cell/μl [300 - 1200]
CD4/CD8 2,3 [0,8 - 2,5]

I'm not on any therapy yet, starting peginf soon. Viral load fluctuated from 5600 to 650 this year. I use supplements like d3, magnesium, k2mk7. Gonna have more tests like IL-2, IL-6, IL-10, TNF-alpha in 2-3 weeks.
Best Answer
Avatar universal
should I start medication with pegintf??

yes

how much Time it will take to clear the virus??

1-2 years on peg, it is not possible to predict the time you will lose it, it can be in the 2 years treatment or in the following 5 years, peg keeps working even after you have finished when you have response
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Avatar universal
no problems, all good for max pegintf response

genotype A and B easier response, D and C worst
Helpful - 0
Avatar universal
srry...There is a correction that hbvdna is 8030.5 not 80305..
I dnt have idea. is there any process to find out gentype?? my doc suggestd me to wait for 3 months..
m very confused about this. what I shall I do??
Helpful - 0
Avatar universal
Hbsag..with end time dillution=1038.8 iu/l

you have a perfect result to clear by pegintf, do you know your genotype?

if you want to clear hbsag i uggest you start supplementing vitamin d3 to reach a intact pth value of lowest norm range, it should be 10-20pg/ml for most machines and a vitd25oh around 100ng/ml (vitd25oh test is valid only if there is no receptors resistance, that s to say pth goes low with vitd25oh 100ng/ml)

start supplemnting vit d3 and let us know results by 3 months, in the meantime some members are trying pegintf plus high dose d3 plus gcmaf, if it will help pegintf response it will be good to add but we have yet to see results, i am the only one until now who tried this combination.this said your low hbsag allows good results anyway even monotherapy

there are some trials showing better results if tenofovir is added too but effect of tdf add on are weak, i am not sure if this will help
Helpful - 0
Avatar universal
please interpret following result.......

Ast=21u/l
ALT= 25u/l
Hbvdna=80305 iu/ml
log value=3,92
hbeg= non reactive (o.39)
Anti-hbe-ab= reactive
Hbsag..with end time dillution=1038.8 iu/l
MRE(elastograpy) shear stiffness= 2.94kpa
please suggest what shall i do with this?
Helpful - 0
Avatar universal
i think only the new micro rna test studied in pisa can give a picture of ongoing immune response


as soon as i get news i will post but the test is probably not available for normal patients not on the studies
Helpful - 0
Avatar universal
is it common that TNF-alpha may be like this in HBV ? My last ALT result was 41 so on the border of the norm.
Helpful - 0

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