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my feedback

hi everybody
here is my feedback from i know that i have heb till now
my biliburine prothrombine all in normal range


  05/06/2011(pregnant)
alt                   12
ast                   09
hbsag              2700ui
adnhbv            2500ui
hbeag and ab not done            
fibroscan          0.16kps
ultra sound       normal

     //11/2011(pregnant)
alt                   09
ast                  04
hbsag            3000ui
adnhbv          <20ui
ultrasound     normal
fibroscan        0.24kp
hbe not done

     03/2012'  (after delivery baby in january 2012)
alt                 16
ast                 12
adn undetectable  <12ui
ultrasound        normal
hbeag        ----
hbeab        ++99%inhibition
hbsag             3500ui
pre c mutant

    12/2012
nearly same results with march2012

     7/2013   (pregnant)
alat        26
asat       19
hbv adn    2600ui
hbsag       3700ui
ultrasound    normal
fibroscan      2.5kp
hbe ag -
hbeab+

january(feeling pains in arms and every where lUck of vit d  17ui
4/03/2014)
alat      166ul
asat       87
adn        44million

24/4/2014
alat   123
asat    65

7/4/2014
alat  111
asat 60

  22/4/2014
alat     169
asat    97

  10/05/2014
alat209
asat 102
adn   54 million

29/5/2014
fibroscan 6.1
  
7/06/2014
alat   156
asat    83

21/6/2014
alat     80
asat     49
fibroscan   7.4

05/07/2014
asat    49
alat     80

26/07/2014
asat    50
alat     78
adn     119 million
fibroscan  4.2

29/10/2014
asat   48
alat    70  waiting for check for 18/11(maybe fibroscan or biopsy)
viral load  80million
thans i  advance  about your opinions





    

  
124 Responses
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Avatar universal
i think what happened is very clear, during pregnancy there is immune suppression by a rise of our own produced nagalase (it has same effect as that produced by hbv or cancer cells but it is a little difference chemically), we produce nagalase only for preganancy to avoid rejection of fetus by our own immune system

so i think hbv rose because of that but slowly by time everything will get back close to baseline because once we stop making nagalase after delivery the balance of immune system/virus should get back close to baseline, unless there are virus mutation immune escape changes

i would monitor hbsag quant, hbvdna and fibroscan to see if everything keeps going in the right direction

i d make vit d3 optimum levels (vitd25oh and intact pth), i d start a diet to make liver repair easier and when hbsag and hbvdna stop the decline i d think about peg or nucs or sequentil first nucs and then peg add on years later

Helpful - 0
Avatar universal
Any comment?especially now I don't know in such phase I am?
Helpful - 0
4 Comments
Your ALT has normalized, but your hbvdna is still a bit high. To get a better picture, you must test your HBeAg. Very likely, you are at the end of Immune Clearance and beginning of inactive phase.  This is just a guess.
M'y hbeag is negative.i was already in inactive phase.then activatin and now maybe again in inactive phase. could I get again in this phase without treatment?and the decrease in my DNA is it significant or not?ths
The decrease in your hbvdna is significant, but the issue is whether it will keep decreasing to below 2,000 iu/ml and stay below under immune control. With your liver in F0, I will observe for another 6 months. I am scratching my head here, sorry I cannot be more helpful.
Thanks lot
Avatar universal
Hi members here are m'y new result
February.          november
Alat 69.                18
ASAT high.           12
Viral load. 17million ui.  Now 199000ui
M'y platelet come finally I normal range.
What do you think members and what should I expect from my doc in my next check?
All other tests are in normal range.
Is the decrease is significant?I don't take treatment only black seeds and hony wich I stopped it last month to see it effect.but I think I will take again.
Your comments please
Helpful - 0
Avatar universal
So thanks god because I don't know what I do if she got infection!
My first son is delivered by cesarean whereas she is delivered normal so I think it is better for infected woman to get their babies by caesarian to avoid blood contact during delivery (just my point of view)
Also during delivery I don't have a high viral load so I ask what really happened?
Thank you for answering
Helpful - 0
Avatar universal
Seems so,

What is the hepatitis B core antibody (HBcAb)?

The HBcAb is an antibody that is part of the virus- it does not provide protection. A "positive" or "reactive" HBcAb (or anti-HBc) test result indicates a past or present infection, but it could also be a false positive. The interpretation of this test result depends on the results of the other two tests. Its appearance with the protective surface antibody (positive HBsAb or anti-HBs) indicates prior infection and recovery. For chronically infected persons, it will usually appear with the virus (positive HBsAg).
Helpful - 0
Avatar universal
Yes I think like that but I gave her at birth the immunoglobulin against hbv with the 3injection of vaccin.does it mean it didn't work?
Helpful - 0
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