My mother was diagnosed with Autoimmune Hepatitis on first week of March 2009 by one of the Doctor (MD, DM – Gastro) in Mumbai.
My mother has undergone liver biopsy and several tests. Liver biopsy and some of the test results are reported below which shows suggestive Autoimmune Hepatitis (detailed report is attached with this email):
Liver Biopsy: Chronic hepatitis with onset of cirrhotic changes; HAI score 3 + 3 = 6, Suggestive of autoimmune hepatitis.
Liver Profile: SGOT, UV with P5P = 85 U/L; GGTP, G-glutamyl-p-nitroanilide = 241 U/L; Alkaline Phosphatase, PNP-AMP Buffer = 158 U/L.
Anti Nuclear Antibody: Positive; Titre = 1:320; Pattern - FINE SPECKLED
My mother has symptoms like abdominal discomfort, acidity & flatulence, constipation, piles, joint pain since 15 yrs and itching & skin rash from last 2 yrs.
Doctor has suggested that the only possible medication is immediate Steroids and Azathioprine therapy. As explained by doctor, steroids therapy can cause various side effects which may lead to different complication during and post therapy.
We are unable to decide whether we should go for Steroid Therapy. We are looking for following:
- Whether the case is a confirmed case of Autoimmune Hepatitis. If any doubt, what are the tests to be done for final confirmation.
- If the therapy is necessary, what are the further investigation/tests to be done before starting the therapy to avoid major complications and side effects?
- What could be the duration and possible steps of therapy?
- What are the possible side effects and recommended precaution for the same?
- What are the observation required during therapy and post therapy?
- Any food or dietary restrictions during therapy?
- Success rate of the therapy.
We understand that this is one of many such requests that come across your desk and greatly appreciate any guidance that you can lend.
Thank you, in advance, for your help. I look forward to hearing from you at your earliest convenience.
Best regards,
Sukumar Nath Roy
Mobile No.: 00971 50 1363931
Email: sukumar.***@****