Sorry for the sarcastic tone, but it is not like I am saying that the original poster is not SVR if he has an AST/ALT ratio less than 1, I just asked. Maybe I expressed myself carelessly in my first post, but I have tried to explain in a better way what I meant in my following posts. I cannot see that I have stated anything incorrect.
"But for the last time, you cannot draw any assumptions from the alt/ast ratio in an SVR patient with normal liver enzymes."
Oops, I guess maybe I am not SVR then after all.
"...but if not, just ask your doctor the signficance of the AST/ALT ratio in SVRs with normal enzymes. But again, the ALT/AST ratio is irrelevant in SVRs with normal liver enzymes. It's nada, nilche, nunca :)"
Note, that my liver enzymes were always within normal range, so I had to find other indications than just having normal liver enzymes to tell me whether I had SVR'ed or not. So since I could not get a PCR until 3 months post, it was very nice to see at 6 weeks post that my AST/ALT ratio was now greater than 1 for the first time since contracting hepatitis C. It was my first indication that I had SVR'ed. So for me not knowing I was an "SVR with normal liver enzymes", it was everything but "nada, nilche, nunca".
Jm: I only mentioned "fibrosis" because some believe you can draw assumptions there.
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Reference was to the non SVR patient with elevated enzymes.
Zazza: Considering the clinical clues I posted above, I would be happy if you would stop saying I am incorrect when you are discussing fibrosis and I am discussing clinical clues to diagnosis. We are not even discussing the same thing.
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Yes we are. I'm saying you are incorrect when discussing "clinical clues" per what the original poster stated. But for the last time, you cannot draw any assumptions from the alt/ast ratio in an SVR patient with normal liver enzymes. I only mentioned "fibrosis" because some believe you can draw assumptions there. Hopefully, anyone interested in the subject will carefully re-read both the original post, your response(s), my response(s), and come to their own conclusions. They might also ask their doctor should they have a good liver specialist.
-- Jim
The reason I find the AST/ALT ratio interesting is because I am curious to if it can help us unfortunate souls who have to wait for a PCR post tx, but do have the opportunity to get liver enzyme readings, to in some way get an indication of relapse or SVR. By asking someone who is SVR, I am trying to find out if in his case what was true for me, was true for him, i e as a hep C patient my AST was always lower than my ALT prior to tx but after tx my AST was higher than my ALT.
Considering the clinical clues I posted above, I would be happy if you would stop saying I am incorrect when you are discussing fibrosis and I am discussing clinical clues to diagnosis. We are not even discussing the same thing.