Failed triple tx with Incivek

[Advocate1955]

My husband failed triple tx with Incivek and is stopping treatment today (4/11/12).

He is:
age 59, Hispanic, G1a, has probably had Hep C for 30+ years
diagnosed in 2007
f1/f2 per liver biopsy in 2007
partial responder to first therapy (SOC in 2007) - had < 2 log drop
f4 per liver biopsy in 2010
partial responder to Consensus Interferon-daily Infergen injections/1400 mg Riba) in 2010, had < 2 log drop
started triple tx with Inc on 9/30/12:  VL's were: week 4 = 78, week 8 = UND, week 12 = UND, week 16-ish = DET<12, week 20-ish = DET<12, week 24-ish = DET 22
All VL tests were done with the Abbott Real Time PCR Assay (Limit of Detection (LOD) 12 IU/mL, Limit of Quantitation (LOQ) 12 IU/mL

Advocate1955

[nygirl7]

Ad,

I really don't know what to say, you've worked so hard and diligently and this is just horribly unfair. I'm glad the all oral non-ifn is looking so promising...there is hope...and we are all hoping and praying for your husband.

I hate this disease I just can't say that enough.

You remain in our hearts, Deb

[ziffy1]

hi,i've read your post and i've felt really sad about it.As I'm on my first tx and I'm very poorly,i can't even think about repeat,you two are a real inspiration for this forum and for fighting for life.You deserve to win this war and I wish that became true at soon possible. all the best Ziffy1

[hrsepwrguy]

So sorry to hear this news, wishing you both all the best moving foward.

[willbb]

Sorry about the news. Having failed a previous attempt myself , I have some sense of how this feels ,however him having failed numerous attempts the impact of this would be even harder.

I personally stay very positive that "Pharma" will eventually get it right for those of us that are the so called "hard to treat "and I know you folks are committed to trying again when the opportunity arises ..as it will..

My best wishes to you both..
Will

[JDB1964]

So sorry for this developement. Stay with us! You are a voice that has helped me and others I am sure.

[Gerbils]

I too am sorry about this turn of events. It is just another reminder that we are all a little bit different in some ways that we cannot see. I wish Incivek had been the answer for your husband. You two are fighters and I hope and pray that he is successful in his next battle with the dragon. Hopefully the next treatment effort will be gentler than the last go around (and will work for good!). My heart goes out to you both. You both have an awesome attitude and are such an inspiration to us all. Please keep us posted.
G