Gilead Trial with Sofosbuvir & GS-5816

[mdudley]

Gilead Sciences:  Twelve week Phase 2 trial of sofosbuvir + GS-5816 (without ribavirin or interferon) for genotypes 1, 2, and 3 treatment-naïve.

The Protocol Number:  GS-US-342-0102
Clinical Trial Number:  NCT01858766

Anyone else in the Gilead 12-week trial with sofosbuvir & GS-5816 (without ribavirin or interferon)?  The initial enrollment was 140 patients and I would like to connect with or hear from anyone else who may be in these trials.  Thanks!

[sljl]

I'm happy to hear of your good news.  I relapsed after 48 weeks of interferon/ribavirin combo and wanted to do the Gilead trials but it does not appear available for relapsers.  

If phase III comes available, I'm wondering if there will be any arms for relapsers.  

sljl

[Meesh813]

I feel so encouraged from your current results.  I've had HepC 2b since 1995.  I've been blessed that my symptoms have, for the most part, been kept at bay and my ALT/AST within range.  There have been a few times, and most likely now, that my VL has been considerably high.  I'm very excited about this drug and the "minimal" side-effects.  If it weren't for the side-effects of current treatments and the multiple horrific stories I've read from others having gone thru the treatment "hell" I might have been more brave to reconsider but I'm thankful I'm in good health for the most part and that I've gone this long without any health issues from this disease.  Awesome, thank you for being a testament to those of us who are waiting in the wings to make a bold step forward to the treatment for a cure!  MRC

[Eduardian]

I just signed up for the sofosbuvir gs5816 12 wk trial. I completed 48 wks
Interferon/ RIBA combo and relapsed ov a year ago. I'm 62 yr old male
Stage 1, geno3a. I start the treatment on Thursday. Good luck to you.
Your results are encouraging to me
Thanks,

[sexygreen]

@mdudey my experience is Identical!!     september 4th will be my first 30 day test after finishing the pill regimen.. fingers crossed..  
same 3A genotype

[his3707]

congrats mdudley.  I know you have put a lot of time and effort into getting a better cure out there faster for everyone!  Best wishes to you

[Eduardian]

I started today gileads 12 wk trial. I'm in the sofo and gs 5816 100 dose group
And no RIBA or interferon. Glad to be in this study.
Hope your progressing well.