Just got my viral Load of week 12. Not good I think.

[yoyoma123]

Hey guys I just got my viral load of the 12th week and I think its not good news.

I started at 8.6 million with genotype 1a and just got my viral load back at 12 weeks at 8,300.

What does this mean. I am not UND? Does this mean I have to do treatment for 72 weeks?

PLease let me know guys. Thanks

[Trinity4]

" It will be even more depressing if you go another 60 plus weeks and don't svr though."

True statement there yoyoma123 and I can speak first hand about that.  

Trinity

[yoyoma123]

I understand what you are saying but there must be people that achieve SVR by not been UND at week 12 and UND at week 24 doing 60 weeks. Since I'm already into it if I keep going for it and it doesn't work its gonna be around when telaprevir will be coming out. I know its a long shot but what if it works. Cause my side effects are very little. Cause I wanna get this over already and telaprevir is coming out like in 2012 and by that time I would have finished and know if it worked so if it didn't I would start telprevir, but what if it works, I'm done and don't have to wait anymore.

[spectda]

I am very sorry that you are not und and understand how difficult this is to deal with. Since the disease moves so slowly you are really in no danger by waiting for 1-2 years for better medication. It will be even more depressing if you go another 60 plus weeks and don't svr though.

- Dave

[spectda]

No liver damage and geno 1a. Any good hepatologist would say wait for new drug. It doesn't make sense to contune. Another 60 plus weeks of soc to give you a low chance of svr or 24 weeks of new pi in a year or two. I don't know why you would consider continuing. I know its difficult to accept, but try to think about the logic.

I wish you the best. Dave.

[yoyoma123]

I'm genotype 1a. I don't have liver damage.

Taking 180mg of pegasys and 1200 ribavirin. I weigh 160 punds.

I'm well informed about telaprevir. But it comes out end of 2011-2012. Thats alot of time. I want to get rid of this since I already started. Or maybe I can do a 48 week treatment even of my chances are very low cause one may never know.

My side effects are minimal. Just some bone pains and that it.

Maybe I can do a 48 week treatment while telaprevir gets closer. Or maybe if UND at week 24 do a 60 week treatment.

Cause my question is this one: If i was UND at week 48 thats 36 weeks more. If I'm UND at week 24 why not do the treatment til week 60, 36 weeks more like the 36 weeks more if UND at week 12. Do you understand what I'm saying.

Why if UND at week 12 just 36 weeks more.
Why if UND at week 24 its 48 weeks more and not 36 weeks more?

[Trinity4]

That's a 3.01 log drop in 12 weeks and no where near UND.  You are responding but not a stellar response to treatment.  Ideally, UND by 12 weeks gives a less than 50 percent cure rate. Not having reached UND by 12 wks, you have lowered the odds to (I think) around 30% even with extending to 72 wks.  You are considered a slow responder and 72 weeks is an option but if you don't become UND by wk 24 stop the treatment or you can stop treatment now and wait for the Protease Inhibitors, liver histology withstanding.

Trinity