Starting Sofosbuvir GS 5885

[Renee543]

Hi, I tried Teleprevir last year and failed. The Institute called me last week to see if I wanted to be in this new study for Sofosbuvir GS 5885. I have not been able to get much info on the net except from the Drug Co.
They have one slot open and I need to be there tomorrow for my bloodwork and EKG. Is there anyone on Med Help that is in this trial or anyone with any info that would help me make this decision. I was so dis-hearted when I could not stay in the Teleprevir study. It is Phase 3, either 12 or 24 weeks and either with or w/o Riba.  It starts next week. Thanks for any info. Reen

[lostdcd]

Hi Mag ,
I will let know for sure.
Thank you again for all your support.
I would also be here all the time following all the postings.
You guys are my best friends(I don't know to use another word here because I feel you all so close), advisor and a place where I could be opened at the time that I couldn't tell anybody how I was.
I even didn't tell my sister,nor my brother because I didn't want to spoil anybodies holidays.
You are my close friends:)
I will let you know when I will have any news
Lost

[Renee543]

You will be :)). I think supplementing is the reason I am healthy. I keep my immune system built up and eat healthy too. Milk Thistle is good to keep the liver healthy and there are other supplements too that really help the liver. I think resolutions have to turn into habits to work.
Let me know how it goes.

[grateful_to_be_here]

EOT results 12 weeks SVR :)

[Geshmit]

A happy and healthy new year to all.

Re diets - I think there are newer schools of thought than 1950s ones about keeping the liver healthy. Our general diet has deteriorated since those years with the advent of processed foods, junk food and corn syrup. I've tried different diets to keep my liver and gut reasonably healthy - macrobiotic, not mixing protein and carbs, no fried foods etc, but I never heard of not eating refrigerated foods. But then again, refrigerators were not as commonplace in the 50s..these days I don't do anything extreme.

In this millennium, I think that cutting out processed and junk foods, eating whole grains and fresh fruit and veg with not much red meat is pretty good for keeping healthy. Milk thistle is also a good supplement for the liver.

Hep B antibodies always show if you've had the disease and cleared it - I don't know if you can have a vaccine if you've already had it? And if you're not travelling to exotic places or having promiscuous, unprotected sex there's no reason to contract Hep B, but different countries have different policies regarding the vaccine. People with Hep C should have the Hep A vaccine - this I know, because if you get Hep A while you have Hep C, it can kill you.

Great news about the 24 week SVR, Renee. I have my 24 week EOT test in a couple of weeks. I'm not sure if they do the follow up observations in the UK, but if they do, I too will take part (that is, as long as I am SVR!).

all the best

[MagTX]

Hi,  I can try to answer your question, though there may never really be a good explanation about your husbands hep b status on his lab findings. If he was indeed exposed to hep b then he would still have those antibodies present, they will remain positive for life. It's hard to answer why he doesn't have these antibodies present now with testing as they are neg. Maybe there was a lab error, which sometimes can and does happen through contamination or by getting another patients results as your own results, in error. Somewhere there was a mistake, that's all i can think of. If it were me I would retest and if these results show neg, antibodies to both hep A and hep B then I would start scheduling for immunizations for both A and B. Also, since you tested neg. for hep b maybe you both can start the immunizations together and get them out of the way. Hep b is a series of 3 injections , it will take 6 months to achieve full immunity, but some immunity begins to show up after the first injection, so that is good. :) you won't need to have the hep a vaccine, you have natural immunity for that one too! You're very lucky, you have nothing to worry about as long as you didn't have a viral load on the hep c PCR by RNA test and only showed pos. antibodies, you're good to go, congratulations!
I have no idea what Dr. Cold was talking about in wanting to re check your HCV status again in one year.... Let us know what he says if you don't mind. All I can think of is that sometimes doctors make mistakes or they are just not knowledgable enough about HCV.    Thanks:)

[lostdcd]

Hi Mag,
Thank you again for your advise. I will ask Mr.Cold why I have to repeat in one year.
I will also let you know about my family results.
PS:
My husband when he was a child (3 years old) had peritonitis and after the surgery he got Hepatitis B.  I know the doctor told me yesterday that there is no cure for Hepatitis B but there is treatment for Hepatitis C. I know just my husband  liver tests were always perfect. They never saw on his blood that he had Hepatitis B. How is this possible? He was tested before for A and B ( like me also, when they told me that I had hepatitis A some time in my life -which I have no clue when) but they said that he never had A or B how is this possible? and he should get the vaccine.

My in-laws kept him on a strict diet for 14 years. I have the book for that diet but unfortunately is not in English. It is a guide how to eat and cook the food for chronic liver disease. The book was printed in 1954. You might say it  is old and not up to date but what  I learned from this book it seems for me that  it is a healthy way of eating and more special how to cook the food on liver diseases. Really hard for people who don't have the time.
I don't know if it is important but my in laws told me that the food that they give to my husband when he was sick was never refrigerated nor re-heated.  His grand mother was cooking from scratch every meal following the recipes in this book I told you about. They gave him just organic meat and vegetables.
This was what I was trying to do  for me(as much as I could) from the time I found out about Hepatitis C . I didn't do it exactly the way they have done it (no time) but I tried my best. The hardest was no salt at all. Instead of salt I was using fresh organic lemon juice -just a little bit. It is the hardest diet I have ever tried to follow on my life. You get used to it but really hard.
Thank you again Mag.

Lost