has anyone been on the trial study for TMC 435?

[cakes8267]

Has anyone participated in the trial study for TMC 435?

[WriteItDown]

Yay Vik! Here's to SVR!

[vik97]

I was in the ASPIRE study which is TMC435 + SOC for treatment experienced patients.  I completed 48 weeks of tx and finished 23 weeks ago.  My 12-week post tx blood test was UND my 24-weeks post tx test will be next week.  My sx were milder than my first treatment with just SOC two years before.  I still have some lingering sx such as brain fog, fatigue and insomnia, but they are mild and getting better all the time.

Vik

[willbb]

Someone else may chime in that is  more knowelegable about this trial..however it would seem odd to me that they would have a placebo arm in a trial for relapsers. Are they doing  a separate trial for relapsers and NR?.Then it would certainly make more sense for you.

Will

[willbb]

world,in my opinion be fairly risk odds.    ..... sorry meant to say   ..    "would in my opinion be fairly risky odds"

[willbb]

Hi there....Yes I had heard also this trial is going to be 33% get a placebo. To take the chance of being one in three to get a placebo world,in my opinion be fairly risk odds.especially in light of the fact  you are a relapser. I also believe you said  in a previous post you had mild st.1 fibrosis.

To me this would not make sense to enter this trial and take a 33% chance of doing exactly the same treatment that you seemed to fail before.when you have time to wait and have a 100% chance of getting the real thing in just a short while.

Always a personal desicion tho
Good luck...

Will

[cakes8267]

I am scheduled to start TMC435 on May 13th.  When you say the placebo is 1/3, thats what I am told, is that considered a high risk for getting the placebo??  
I am excited to start this treatment, but am very afraid I will only get the placebo.  I am a relasper and I want the real thing.  
Thanks for your input "writeitdown" also.