incivek failed

[Roberttherock]

I just received bad news.  I finished treatment with incivek in Jan. received 6 mo blood test, relapsed.  I was undetectable at wk 4, 12, and post tx.  I am just totally crushed.  I have no idea what to do next.  This was  much tougher to deal with than previous treatments.  I was so hopeful. I hope the rest of you get a better outcome.    

[MeWithC]

x0x
;)

[libzo2]

You have an amazing, inspiring attitude.  Thanks for the info.

[libzo2]

It's not bloody fair.  I want to throw up.  I am sheetlessly scared of the same result.  On purpose, I have avoided my Doc and this place because of this fear of being smacked with the 'back where you started' card.  You are incredibly brave, the rock.  I am jello and haven't even found out yet.  I am on the fence wondering if this lost child within can ever come home to stay.  I am so sorry for you and your family.  Thank you for letting us know some of your path on this wretched journey.  

My date of truth is in Sept.  I am still holding my breath.  Robby - What advice can you give us chickens?  What does this mean to you?  

[Dee1956]

Oh my God!  I am so shocked and so sad for you, I hardly know what to say. I have relapsed in the past, know how it feels.  I am just so very sorry.
When I relapsed, Dr Dietrich told me to rest, heal my body and spirit, wait a year and try again when new drugs came out.
I just feel terrible, you worked so hard and you are right, this last tx was the worst.
My best to you
Dee

[zako7]

Robert sorry to hear about your relapse. I think that the new drugs in the pipeline will improve svr numbers significantly.
I would like to get something cleared by you. Have you treated before in the past before treating with Incevik? If yes, I thought prior relapsers and non responders are treated for 48 weeks instead of 24 weeks.

[Advocate1955]

Robert, so sorry to hear that you relapsed.  As others have said, maybe you can re-test right away to be certain that it is a relapse.  Make an appointment to see your treating doc and ask his/her opinion, but as others have said, it is very likely that you have either a more resistant virus and/or you are a poor responder to Interferon.  I'm so glad to hear that you only have moderate liver damage, by that I'm assuming that you mean f2 or so?  And I agree with OH that your liver got a wonderful break for 6 months, which will have helped.  But because of your age, you are at a higher risk for more rapid progression of fibrosis and/or for developing liver cancer.  I would recommend that you ask your doc if he/she would see you more frequently, perhaps every 6 months to once a year, and if he/she would order more frequent labwork, perhaps every 3 months, to monitor your liver function closely.  Not sure if/when your doc might want to do another liver biopsy to check on your fibrosis, my guess would be every 3 years.  You may want to ask your doc if he/she would consider recommending you for any all oral trials that may come up in the next two years or so.  Or you can search clinicaltrials.gov.  Otherwise, hopefully it won't be a long wait for the new all oral meds, and hopefully you won't progress to Cirrhosis.  In the meantime, keep doing what you're doing, give yourself time to process this new piece of information about relapsing, stay alcohol free, drink coffee, eat liver healthy food, exercise, maintain a good BMI, and avoid meds that are non-essential and supplements that your doc hasn't approved.
Take care, and hang in there.
Advocate1955