Aa
Aa
A
A
A
Close
Avatar universal

non responder

Can you going through treatment again after being a nonresponder & is treatment successful second time around.
I went from 2,000,000 viral load to 25,000 in a three week period. After 6 months I was at 5,000 and the doctor took me off the meds. I protested along with the nurses but it did not matter. My biopsy was stage 1 after 38 years with the virus.
I,m hesitant to go through the treatment again with the same results.
Danny
2 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Sorry,but as i understand this,you are a "nul-responder"...this means you have never went UN on this type of tx...studies prove your odds are very low to clear with PEG and RIBA,which is what i persume you were on...looks like you need the Teleprevir or Boceeprevir drugs in combo with the SOC drugs....this is my take on this...BTW..im a slow responder ...i cleared at week 12...if you dont clear by wk 24...another option is too to daily meds  called interfergen...which is a tough tx..you are very lucky to bs a stage 1....good news...get in on one of thr trials...they are available


r.s
Helpful - 0
Avatar universal
If you dropped 2 logs by week 12, i e down to 20'000 IU/ml, you would be a partial responder since you were not UND by week 24.

I figure you got a good chance of clearing if you add a protease or polymerase inhibitor to SOC, since you obviously respond to interferon albeit not enough. Getting into a trial might be a good idea, as long as you are certain you are getting the new drug as well and not just standard treatment.

With such a good biopsy result you can also wait until the new drugs are approved. Hopefully that will not be too long, perhaps 2011.
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
Can I get HIV from surfaces, like toilet seats?