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2094297 tn?1345389093

started to feel horrible and very grumpy

  I started to feel really bad and felt like my personality had changed (for the worst), acting very snippy at everyone.  I work in sales so this is not a good thing , and i have two small children.  I have hep c , and have had for over 3o yrs., but i have not sought treatment because 4 yrs ago when biopsy was done i was told it was very mild and non aggressive.  My new results just came in and my alt level was at 690 and my ast was at 216 .  I am very worried right now , I do have an appt to see spec. next week.  I have been having really strange things happening , I feel like I am in a bubble, and when i look at things they seem to move like a vapor, i cannot get enough to drink and i cant seem to pee enough, my throat also seems swollen  and my voice is changed. i also have diabetes type 2 was has went from 6.5 to almost 10 on the a1c test , has anyone else been where I am, what is happening ? what should I expect ? if anyone could offer any help would greatly appreciate it ......
Best Answer
87972 tn?1322661239
Constant (or nearly) urination and thirst are both hallmarks of type II DM. If you’re A1c results are brushing 10.0 now the doctor will likely want to get this controlled prior to initiating HCV treatment. I really can’t comment intelligently on the other symptoms you mention.

Hopefully you’re connecting with either a GI or hepatologist next week. If you haven’t had a liver biopsy for four years, they might recommend another to see if fibrosis (scarring) has progressed. They’ll also probably order blood tests; CBC, compressive metabolic panel, etc. In fact, you might want to call their office today and see if they want to order labs in advance of your appointment next week; that way you could go over these with the doctor.

With liver enzymes elevated like that it’s likely you have some activity going on, but it’s hard to draw any conclusions based on those results. The other tests mentioned above might offer more diagnostic data.

Do you know what genotype, or strain of HCV you have? There have been advances in HCV management over the past few years; there are adjunctive drugs added to the original interferon/ribavirin that are make treatment more effective for select genotypes.

Good luck, and let us know how the appointment goes. Keep eating those nasty trolls-

--Bill
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2094297 tn?1345389093
  Thanks .....
Helpful - 0
2065676 tn?1331422440
I do understand. It is quite the emotional pull to be so happy to finally start treatment and I was so terrified of the what ifs. I too am very hypersensitive and in touch with how I operate. I decided to ahead with with it all as I had a perfect window of time, FINALLY, in my life to take care of me. This is such a wonderful site for information, encouragement and support. Best wishes....
Helpful - 0
2094297 tn?1345389093
   Great to hear that you have not had too many side effects, I have been very worried about it as I seem to be very in tune to my body and feel things easy
so thanks for positive post as I am afraid of what will happen and excited to get it started if that makes any sense....
Helpful - 0
2065676 tn?1331422440
Great job of getting your pre treatment exams completed. I use the incivek and will hopefully only have to take for 12 weeks instead of my full 24 week treatment. Will be nice to be down to only 2 meds...Have just started week 6 without any real sides YET. Best wishes :)
Helpful - 0
2094297 tn?1345389093
  My bad, I will be doing the triple tx it will be pagasys and riaviran and incivek
I am just so new to this and was looking at just a box they had given me, so I guess I need to revise my question .... are these the recommended meds or is their something else I should be aware of , they did give me a choice between incivek and something else but the dr recommended incivek... thanks for helping me.....the victelis was the other one...I am going to choose the incivek... is that what others have done ?????
  By the way had colonoscopy this morning and all went well, they did find two small polyps and removed them dr. said nothing to worry about.


I tried to teach a troll to spell but he could'nt so I ate him,,,,
Helpful - 0
1840891 tn?1431547793
I'm guessing that maybe your doctor rushed a bit in describing the tx options. Genotype 1A is a stubborn one to treat, and the success rates with Pegasys alone are abysmally low. The success rates with Pegasys and Ribavirin together got a lot better but were still not great. Many of us (including myself) went through both of those treatments and still had the virus. It's only since they added one of two new protease inhibitors to the mix that success rates started to be really good. That means a triple tx. Both versions include Pegasys and Ribavirin, but one version starts off the therapy by adding Incivek (also known as Teleprivir) for the first 12 weeks, and the other version starts off with just the 2 drugs but adds in Victrelis (also known as Boceprivir) later in the tx. Does this sound like what your doctor may have been trying to say, and are you seeing an actual hepatologist for tx?
Helpful - 0
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