"I just had my blood taken and it all comes back as usual for my thalassemia."
Hi, I take it that you have normal range WBC and absolute neutrophils? If so, that's your biggest clue. With CML or infection, you'd expect some high counts on a CBC test.
An alternative possible cause for you is some systemic inflammation.
Or we could think this way: Blood cells (such as granulocytes) are made in the bone marrow. Thalassemia intermedia can cause the marrow to get over stressed, from having to compensate for the thalessima. A stressed/inflamed marrow might be causing your high immature granulocytes.
Let's look here: http://www.clinlabnavigator.com/immature-granulocytes.html
"Usually an increase in IGs is accompanied by an increase in the absolute neutrophil count. However, elderly patients, neonates, and patients with myelosuppression may have elevated IGs without an elevation of the neutrophil count."
You're not elderly, not a baby. But "myelosuppression" refers to the bone marrow.
Another important factor: why did the doc run the test for immature granulocytes in the first place? You say you have no symptoms.
Also:
"However, my immature granulocytes is high. Normal is under 2%."
Yours isn't as high as 10%, correct? What's your number?
Don't hesitate if you have any followup questions.
Susan, I should add that CML is not hereditary.
That is said by the American Cancer Society and at many other places:
"CML does not run in families."
https://www.cancer.org/cancer/chronic-myeloid-leukemia/causes-risks-prevention/risk-factors.html
Here's how I would look at things at this point:
You don't have the typical signs of CML. But the high-ish immature granulocytes are odd enough so that a visit with the hematologist is a good idea - as the chance to rule out leukemia and set your mind at ease. Then the next task is to figure out what is really happening, such as maybe investigating what's happening in the marrow.
It's even possible that your immature granulocytes will be back down by March.
I hope you're doing well with the thalassemia and your iron is under control.
Did you have a transfusion lately, that might have set things off?
You can paste your CBC results on the forum if you remove all identifying info of yourself and any doctors. Or you can send it in a PM to me. Or if you have an image, you can post that in your profile here with identifying info blacked out.