It is been almost a month that my husband has been struggling with elevated liver enzymes and elevated lymphocytes. The AST level is above 300, AST is around 200. Lymphocytes 22%. Neutrophils normal. Bilirubin normal, TG normal. He was admitted couple of times for severe headache and the elevated liver enzymes. He had spinal tap so meningitis was ruled out. Hepatitis was tested and all was negative. He was partially positive for Lyme but when retested he showed negative. CT on abdomen, MCRP on abdomen normal. MRI on head normal. Slightly elevated for CMV virus. He already had mono as a kid so they say no way he can have it again. He was on Doxycycline in hospital IV for a week, then followed up with oral doxy when he was at home for another week. While in hospital and on IV antibiotics the ALT and AST came down little bit ALT came to 200 and AST came to 150. But one week after he was discharged, he went for blood work to check the enzymes and they went again above 300. He doesn't have a headache anymore and we thought he was getting better, because he feels better yet the enzymes are high up again. Doctors are struggling with diagnosis. Any suggestions. He is seeing hepatologist in 2 days.