Hello and welcome to the forum. I'm sorry to read that this is happening. Anyone who suffers chest pain and tightness should be evaluated as soon as possible by a doctor. You really need to rule out a cardiovascular reason for this. Once you do that, you can look at other reasons people wake at night with chest pain and tightness. Things like acid reflux, anxiety, issues with cartilage in your ribs, gall bladder or pancreas problems. However, because this could also indicate angina or heart attack, you should be seen by a doctor. Here I some information on angina. https://www.webmd.com/heart-disease/heart-disease-angina Please let me know what your doctor says.