Can mild maternal hypercalcemia cause placental calcification ?

[waitn2b]

I've been reading about placental calcification and can't seem to find an answer to this question. I've had mild hypercalcemia for a few years and have aslo had 2 late miscarriages (consecutively) at 18 weeks. Can hypercalcemia cause placental calcification or am I way off track ? I don't smoke, so that's not a factor. Except the elevated calcium (usually about 10.9 to 11.0) I am a healthy woman who has had healthy, uncomplicated pregnancies before this calcium issue. Could the hypercalcemia lead to early placental calcification in the second trimester leading to these "missed miscarriages" I've had ?

Also of mention is that I have had explored all other possible causes, everything always comes back negative, including chromosomal karyotyping of fetus, and parents.

[mikaleen]

Hi. I'm sorry for what you've been through.  Has a cause been found for the hypercalcemia?  I had an elevated level once and I was going to be tested for a parathyroid tumor which is the most common cause for higher calcium levels.  When I was doing research I found that it's a simple condition to cure but if it's not there's a high risk of miscarriage.  I don't know about placental calcification though. My next test showed normal levels though so that wasn't the cause of my two m/c.  You can google parathyroid disease and miscarriage, and it will bring you to a site about high calcium during pregnancy.  Good luck!  

[bam1014]

I'm very sorry for your two losses.  Like steph, I really don't know anything about this.  Please feel free to join us, post or keep us updated.

[steph9803]

I'm so sorry that you have had to go through that... I really don't know anything about this. But this will bump it up so maybe somebody will see it that knows more about it. Sorry I couldn't be of any help. I hope you can find some answers though.