CSF Results

[Chris_1234]

Hello all,

I was wondering how many other people with MS has seen an increase, such as mine, in CSF protein, WBC, CSF Albumin, CSF IGG?

CSF Total Volume; 9.5ml
CSF Appearance: Clear
CSF COLOR; COLORLESS
CSG SUPER NAT; COLORLESS
CSF WBC; 28
CSF RBC;  1
CSF LYMPHS 0.98
CSF OTHER CELLS; 0.02
CSF PATH COM; Moderately cellular cytospin preparation containing lymphocytes, scattered plasma cells and monocytes. Rule out infection, inflammatory process, degenerative disorder, etc. Clinical correlation is required.  Suggest flow if lymphoproliferative disorder is suspected clinically.

CSF GLUCOSE; 3.2 MMOL
CSF PROTEIN; 0.90 G/L
CSF ALBUMIN 0.52 G/L
CSF IGG; 0.163 G/L
CSF IGG/ALB RATIO 31%
ALB INDEX 12.4

IGG INDEX 108
SERUM IGG 12.2

PATTERN; Several bands of varying concentration seen in CSF (but not serum) follow IEF-IGG immunoblotting.  Oligoclonal banding pattern, frequently seen in multiple sclerosis.  Elevated albumin index is suggestive of increased permeability of the blood brain barrier.

[HVAC]

I agree with Immisceo.

Alex

[immisceo]

Hi Chris! When most of us have an LP in the context of an MS diagnostic work-up, the only result we're interested in (as MS or potential MS patients) is this bit:

"Several bands of varying concentration seen in CSF (but not serum)" I assume from the next line that the bands in question are Oligoclonal bands. This points towards MS as a possibility, but it's also not the last word.

Usually a neurologist will take these results in conjunction with MRI, clinical exam, blood test results, patient history, etc to make the final diagnostic call. Obviously, there may be other results there that would be of interest to your medical team, but as someone diagnosed MS, anything other than the quote I pulled out is basically Greek to me because that's the only part they were really looking for.

Hope this answers your question. Sorry a response took a little while. Weekends can be a little slow around here. Aside from whatever caused you to need an LP in the first place, I hope your weekend is going well!