MS is beyond tricky to diagnose it seems. I think lots of people want to say no, it's not that but in reality, all people are different. "Most" is just that, most. Not all. So, I think still keeping MS on the page to keep looking into makes sense for you. I'll have to read your other posts to see what your symptoms are. Hope this gets sorted out for you and soon.
Technically it is still possible to be diagnosed with MS without Obands but you need to keep in mind that it's very uncommon and these untypical pwMS would still have more than enough consistent objective evidence to be dx with MS even with out the Obands.
You've mentioned that this started almost a decade ago in your teens, that you only have a few non specific brain lesions and they're not in MS suggestive locations, and that you don't have any Obands, so imho it looks like your diagnostic evidence is actually pointing away from a neurological condition like MS and your best direction to look at is what's associated with small fiber neuropathy....
"Small fiber neuropathy can be the first sign of an underlying condition, such as diabetes. Other conditions that may cause small fiber neuropathy include:
endocrine and metabolic disorders
hereditary sensory autonomic neuropathy
immune system disorders
inflammatory bowel disease
mixed connective tissue disease
Other causes may include:
certain medications, such as chemotherapy drugs
vitamin B-12 deficiencies
An underlying cause isn’t always found. In these cases, small fiber neuropathy is considered idiopathic."
Hope that helps.....JJ
Hi. I’m brand new to this community. I was diagnosed with MS in 2006. I didn’t see in your posts whether you had an MRI of your spine done. I’ve had all the symptoms, and more, that you described with the exception of the head and neck tremors. However, symptoms can vary quite a lot from person to person with MS. And as you already know other diseases can cause similar symptoms. When I was diagnosed they had to do MRIs of my spine as well as my brain. MS lesions can happen in both locations. Finding lesions in both the spine and brain would help clarify or make the diagnosis. I don’t know how your doctors can make an accurate diagnosis without MRIs, with and without contrast, of your spine!
Empathizing with your frustration,