Neuro said, "Bilateral subependymal nodularity" is part of MS - but is it???

[JemmAus]

Saw my neuro the other day. My latest MRI report said on top of demyelniating lesions that I have "bilateral subependymal nodularity". Neuro pointed to the corpus callosum and said "it's in there, see". I FORGOT to ask if it was there last MRI (wasn't reported last MRI) so don't know if it is new or not.

Anyway, he reckoned it is  "part of MS". Yet I can find NOTHING in any MS info about this. I ca find it relating to epilepsy, brain tumours and "tuberous sclerosis" (which sounds awfully unpleasant). But not for MS.

I asked Quix a while ago and she was unsure as well.

Has ANYONE had this reported on their MRI and their neuro declared it "part of MS"??  

Its sending me mental.

[jensequitur]

I don't think it's part of MS - my previous research led me to believe that it's an artifact of the way the brain grows.  In other words, when your brain is forming, it's misplacing bits on the left that are supposed to be on the right.  Basically a birth defect.

It's possible that the misplaced tissue is causing problems, but it wouldn't cause the MS.

[Quixotic1]

I know nothing of this entity and would have to do the research that JJ apparently has already done.  Thanks, JJ.

Q

[supermum_ms]

Hey Jem,

I wouldn't necessarily think this is anything significant, just from my quick google searches it appears to be even something you can be born with, no huge red flags of note. It does appear to be most commonly related to epilepsy, the 2 studies i found that mentioned MS, actually excluded MSers from the study so not that helpful.

Correct me if i'm wrong, but i thought you were having epileptic events associated with your MS presentation, adult onset as opposed to child onset, so it seems reasonable to conclude that this is connected to the MS and not something additional to worry about. I dont know if this has happened but he could of been refering to the corpus callosum area (lesion) being part of MS, not specifically the bilateral subependymal nodularity being part of MS, just a thought.

"The subependymal zone—like a beating heart—continuously sends new cells to different areas of the brain: neurons to the olfactory bulbs and glial cells to the cortex and the corpus callosum. Interestingly, the generation and flow of cells changes in response to signals from anatomically remote areas of the brain or even from the external environment of the organism, therefore indicating that subependymal neurogenesis—as a system—is integrated in the overall homeostatic function of the brain."

Seriously, i wouldn't be concerned.

Cheers..........JJ

[Udkas]

Hi there,
Only sending you mental (lol).  Well I have decided I am already mental!!! I hope someone can answer your question soon.  

Can or do you have a case manager allocated?  I find If something is really bugging me I can ring my case manager and she will write down my question and either get my neuro to email me, ring me or tell her etc. as you always wish you could have asked more questions when you are there.

My bladder is driving me mental today and yesterday, million trips to the loo!!  Urgency is crazy, and I had the worst nerve and back pain, getting spasms in my urethra too, and pins and needles in my stomach, grrrrrrr, as I have been so long and so good I am wondering if this is the start of a flare, as I had a flu thing last week, but over that now.  I must admit I am feeling a bit depressed, you think things have gone away and then they come back to haunt you. Hmm sorry Jem, venting on your post!  How rude of me!!!!

Hugs to you, I am so pleased that you have been feeling a bit better. Sorry for whining on your post!!  I hope someone can answer your question soon.

Hugs,
Udkas..xx