Aa
chemo meds
my mom is on Ifex, doxil, mesna, and ethyol...is anyone familiar with these drugs for chemo?
No I haven't...actually I know nothing about what is typical. My mom had ovarian sarcoma and the doctor really went out of her way to tell us how rare it is.
Is your mom on first line chemo or second line? First line is traditional Taxol and a Platinum based drug.
Doxil is fairly new, but is only Doxorubicin encased to help it stay in the system longer...it's a second line (salvage) chemo that is very popular. Ifex is also a second line chemo approved for ovarian.
Mesna is an antioxidant which, in cisplatin (platinum based chemo) chemo, protects the ovaries in research studies in lab rats. Typically, however, most women do not have their ovaries when on ovarian cancer treatment. There is other research showing it's use with Cisplatin and some promising effects.
Ifex (ifosfamide) is used with Doxil in some cases, and platinum based in others, for second line salvage chemo with positive effects.
Ethyol is used for women who have repeated doses of platinum based drugs, such as cisplatin. It's use is a 'chemoprotectant' to help minimize the damaging effects of chemo, mainly in the kidneys.
I'm actually surprised to see an oncologist suggest and give all of these...without knowing your mom's complete history, it actually looks like the oncologist keeps up with the research journals and is trying some innovate stuff, or mixing some common second line chemo (doxil, ifex) with other research. Have you discussed with the oncologist why they are suggesting the following chemo?
Doxil is fairly new, but is only Doxorubicin encased to help it stay in the system longer...it's a second line (salvage) chemo that is very popular. Ifex is also a second line chemo approved for ovarian.
Mesna is an antioxidant which, in cisplatin (platinum based chemo) chemo, protects the ovaries in research studies in lab rats. Typically, however, most women do not have their ovaries when on ovarian cancer treatment. There is other research showing it's use with Cisplatin and some promising effects.
Ifex (ifosfamide) is used with Doxil in some cases, and platinum based in others, for second line salvage chemo with positive effects.
Ethyol is used for women who have repeated doses of platinum based drugs, such as cisplatin. It's use is a 'chemoprotectant' to help minimize the damaging effects of chemo, mainly in the kidneys.
I'm actually surprised to see an oncologist suggest and give all of these...without knowing your mom's complete history, it actually looks like the oncologist keeps up with the research journals and is trying some innovate stuff, or mixing some common second line chemo (doxil, ifex) with other research. Have you discussed with the oncologist why they are suggesting the following chemo?
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