daughters getting ovca

[rstcst]

My mom has ovca and I am wondering what the risk is of her daughters getting it.Also would it be worthwhile to routinely to get a ca125 for us.

[sandee3]

Good advice from Jeanne.  I am BRCA 1 positive.  BrCa @ 39 yrs old now OvCa stage IIIc at 49 yrs old.  Tested positive in Jan  08 after Dx of OvCa.  I have two daugthers--one tested positive, one negative.  Positive one is 24 yrs old and is having mastectomy this summer, then..hopefully a baby followed by a hysterectomy.  Too bad I did not have the BRCA test when I requested it 10 yrs ago.  My Onc thought that it was too expensive and then, "What really would you do with that information?"  

Perhaps consider having a hysterectomy!!!!  For Pete's sake!

Sandee

[momofsandj]

Your mother should be the one having the testing -- if she doesn't have any BRCA mutations then your sisters will be at no higher risk than anyone else -- if she does test positive then you and your sisters should be tested for the gene.  I started getting CA125 and level 2 ultrasounds at 31 and found my ovaca on a ca125 when I was 43.  My sister died of ovarian cancer and my mother had breast cancer.  After my first recurrence I got tested and was BRAC1 single mutation positive.  It puts my daughter at a 50% risk of picking up the mutation and if she has it, a 50% chance of getting ovca.  She's only 13 so I can't test her but she knows the rules:  finish college, fall in love, get married, get pregnant have kids, have hysterectomy.  If I'm around when she turns 18 and she's emotionally ready to hande it, I'll have her tested and then maybe we can all relax a bit.  But she will still have to be screened regularly anyway, because you never know.

Jeanne

[StillFighting]

If you are concerned about it I would have the testing done reguardless of family history. There is no history of it in my family and yet I've been battling it for a long time now.

Good luck to you and your mom.

[melenzbee83]

Hi,
I agree with the first posting you need to get a brac testing to see if OVCA runs in your genes. This may not be the case however.

Best of luck

[bohan54]

Talk to your gynecologist about your mom`s dx and hopefully he or she can give you some good advice.  My sister had a transvaginal ultrasound after I was diagnosed, it is a bit better of a screening tool for pre menopausal women.

Sharon

[jlock]

Since this is your Mom there is a chance of your getting the ovca as well.  You could go for brac testing which would look for the gene for ovca,breast and colon cancer. That is where I would go for if I were you.  A ca-125 is ok but has so many false-positives to be dependable.  Good luck~~Joanne