Hello Just Another Patmer, it is very interesting what you mention. If you click on my previous post you can read that I have already talked about one of the most important things that is INFLAMMATION. I think we are closing the circle more and more and although this is a genetic disease, it seems to me that we can minimize the side effects. It seems to me that the key here is called "HLA-B27" and "TNF-α".
I have been doing research and there are very specialized drugs that inhibit "TNF-α" for people with serious problems with this. However I found a page that a person created, where he talks in detail about factors and things that inhibit and can increase "TNF-α". He puts the links to official publications, in everything that he is writing. He left the page for you to start reading:
https://selfhack.com/blog/supplements-lifestyle-factors-influence-tnf-interleukin-6-il-6/
I am clear that this type of inflammation is causing the intestine to fail to recover. There is something that caught my attention on this page when he talks about "TNF-α" enhancers:
------- THE LECTINES ---------
This is extremely interesting, because we were focused on sugar and candida, but Lectins can be the change to drastically reduce the symptoms of PATM.
I need to read more about lectins, but there are articles where they criticize them.
I would like us to read all about Lectins and try reducing as much as possible, the foods that contain these (which are many by the way) and follow some things that the page mentions, so that the intestine could repair itself. This may be the light at the end of the tunnel.
Finally, I would like to tell you about an anti-inflammatory that I have personally tried and that has helped me reduce the symptoms of PATM, which are evening primrose oil capsules. I have also tried borage oil capsules. The secret of these oils is the high content of GLA (gamma-linolenic acid), which are also capable of reducing "TNF-α", this was what convinced me more of this than I have spoken.
The detail is that although I took the oil capsules with GLA, but on the other hand, I did not stop eating beans, and in fact it felt like when I ate beans, more mucus went down to my throat, a symptom that the inflammation was on its way. What I am going to do from now on is take the capsules that I previously had left over, but I am going to suppress the lectins as much as possible. Other things that the page talks about with its respective link to PUBMED and that convinced me is Nicotinamide and some FLAVONOIDS
Please take a look at the page and comment, regards.
I had come to a similar conclusion before because I had personally taken some supplements which were supposedly to improve my immunity but my patm instead flared up worse than ever. Alternatively, the things that seemed to lower my immunity also lowered my patm. Therefore I concluded that patm airborne compounds might just be one or more inflammatory cytokines themselves because of the way it causes extreme allergic reaction on other people from very far away. It only needs a small amount of airborne concentrated gas.
Oddly, HLA-B27 is an antigen itself and while it can trigger autoimmune response with patmers, perhaps it’s actually causing inflammatory cytokines to spike in our blood and gets airborne. The other hypothesis is that HLA-B27 is the actual mysterious PATM airborne compound we’ve been looking for.
If it’s in high concentration within our blood, it’s possible it can get airborne via bodily secretion or breath. Small broken bits of the protein can likely get airborne and cause reaction on other people.
It’s also possible that we may be producing different antigens but cause similar allergic reaction in other people.
Please everyone, lets try and get tested if we’re producing the same antigen ‘JustAnotherPatmer’ does.
I have chronic inflammation in my gut with erosion. I figured if this is the only thing the doctor can find wrong with me, then this is the problem It is in my nose and the as well.