Hello.
Is your husband overweight ? If yes, has he been given any weight loss plan ? OSA is an independent diagnosis. But there are many factors which contribute to it. And one of them is the weight.
Depression is a co-morbidity. It is very important that he overcomes his depression. Is his depression still untreated ?
All these symptoms are inter-related. They increase each other's severity. Untreated depression leads to a disruption of the sleep architecture, which can worsen the OSA.
And to comment upon the CPAP, I would like to mention that CPAP is not always useful after the UPPP has been done. He may, however, benefit from oral appliances.
The most useful way of helping him get used to the mask is to have him understand the implications. The side effects have to be weighed against the benefits. Once he has the insight, he will get used to it.
You will have to do a lot of talking.
Regards
BTW, I forgot to ask. When you say your husband has tried many masks, were they all from Resmed? The masks do take a while to get used to. I find the Mirage Activa works well for me, but it has a strong exhalation port.
His UPPP surgery has complicated his OSA. xPAP is not very effective when this surgery has been done. The other surgeries may also be playing a role.
OSA and depression are tied together. If you can't sleep well for an extended period of time, you;ll become depressed and down. You can develop anxiety as well as a result of sleep deprivation. His ENT specialist wont do anything for him, sadly. He needs to see a sleep specialist.
Bottom line, fix the sleeping problem, he'll feel better all around.
Good luck.