There is a rare condition known as TSH-secreting Adenomas. "TSH-secreting (thyrotroph) adenomas are tumors of the pituitary gland that secrete thyroid-stimulating hormone (TSH)". With this condition, a person who has a thyroid gland will produce too much thyroid hormone if his TSH is too high and he would become hyperthyroid.
If you are seeing an endocrinologist next week, you should discuss this with him.
Just more proof that TSH is virtually worthless!
Hi, thanks for all replies. Prior to TirosiCnt 125mcg, my TSH was in the 20's, highest was 28.8,. 125mcg brought it down to 6.2 and now 137mcg 1.9,. Prior to Tirosint, my TSH was up/down like a roller coaster. Strange thing is since TT, my FT3/FT4 always stayed consistent, only TSH fluctuates. That's the mystery. What's causing my TSH to go wacky. Labs in the morning, endo appt next week.
Hi AJWS,
It would seem like the obvious thing to do would be to go back to 125 mcg T4, because at that dose you did not have any hypo or hyper symptoms and your FT3 lab was reasonable at mid-point of the reference range. It may give you some comfort to know that doses of 100 to 125 mcg of T4 are the most common used.
It appears that you or your doctor did not like the TSH of 6.2 on the 125mcg dose, and raised your dose to 137 mcg and that has precipitated numerous symptoms. On reviewing your posts going back to 2015, I see that you have recognized (but not your doctors) that your TSH has been high and not in synch with your FT4 and FT3 readings going all the way back to 2015. I don't know why that would happen and it would seem that your doctors don't have any explanation either. I think the logical thing to do would have been to base any dose changes on your symptoms and your FT3 level.
If it was me, I would go back to 125 mcg and continue to monitor your symptoms and the TSH, FT4 and FT3 labs. On your last labs on 137 mcg, your TSH was much lower than it has been (1.9). This might be an indication that whatever was going on with your TSH has resolved itself and you may find that your next labs for TSH on 125 mcg is in the normal range and in synch with the other labs. Let's hope so.
If you had virtually no symptoms, why did they raise your dosage in the first place?
First rule should always be, if it isn't broke, don't try to fix it.
How long were you on 125mg tirostint before you switched to 137mg? Maybe having a high tsh for a long time and then having a drop in tsh from new meds causing you a little grief until your body adjust again.
I'm sure someone with more knowledge will be here soon to answer.