Hi
Welcome to the MedHelp forum!
Generalized body edema can be very serious. It can be due to severe anemia, a failing heart, serious kidney disease, liver failure, electrolyte imbalance, polycystic ovary, low protein in the blood, and disorders of adrenal gland. This is something for which you must consult a doctor ASAP, preferably an internal medicine specialist. Please let me know if there is any thing else and do keep me posted. Take care!
I am assuming she has seen a kidney doctor and a heart doctor? If not that would be a place to start. Also as stella said thyroid and adrenal problems can cause such a thing. What other symptoms does she have?
Bloating is common for thyroid/adrenal disorders. Inflammation is a reaction to hormonal issues. You can visit the thyroid board and see if she can relate to anyother issues posted there too.