Nobody has tried everything -- there are so many meds out there and so many treatments and so many different therapists, but I do understand that when this lasts a long time it just doesn't seem worth it anymore. But I'm guessing you don't really want to go into a coma. I'm guessing you're really hoping someone can make you feel better. I'm in a similar place, but nobody's going to put you in a coma for the rest of your life and I think you know that. You just gotta keep trying and find things you like to do and do them and try everything. If the docs haven't helped you, try natural medicine. If that doesn't help, try moving to a different place if your anxiety allows you to do that. If you have a job that doesn't move you, find a different job. If there are things you always wanted to do and you're at that point in your life where you feel you have nothing to lose, well, now's the time to do them. Peace.