I'm a 30yr old male. I was on Sertraline approx 10 years ago for depression and it seemed to work until a crash. For one reason or another over the years, my treatment has changed several times. It is 2011 and i have found my way back to sertraline. I am currently taking 10mg of buspirone 2x day and 15mg of mirtazapine for major depression and generalized anxiety. I have been feeling constantly tired, apathetic and despondent. My psychiatrist prescribed a starting dose of sertraline of 50mg/day. Since starting the sertraline again i have been suffering from physiological anxiety symptoms such as a tight throat, lump in throat, trouble swallowing and breathing, etc.
Is there an existing drug interaction between Sertraline and Buspirone and/or Mirtazapine ? Or can a person's toleration of a drug change over time?
I am also dependent on imovane/zopiclone to be able to sleep.