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Genetic Disorders Forum
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Autistic Siblings

I have a grown son who is autistic / mentally challenged. My daughter has an IQ in the 140's, and is recently married. If she has children, is there a higher risk of her having a child with autism? Is there some kind of genetic testing that can be done before she and her husband make a decision on having children?
1 Responses
886824 tn?1253740254
MEDICAL PROFESSIONAL
Autism and developmental delay are complex disorders with both genetic and non-genetic causes. About 10% of people with autism have a genetic condition that may or may not be inherited. There are numerous genetic conditions that can cause autism and/or developmental delay, including certain chromosome abnormalities and Fragile X syndrome.

We recommend that your son meet with a clinical geneticist for evaluation. A clinical geneticist can perform a detailed physical exam and may order tests to help determine if there is a genetic cause for your son's behaviours and problems. This information may be informative to other family members, especially your daughter. A medical geneticist can be found at the American College of Medical Genetics website.

We recommend that your daughter and her husband meet with a genetic counselor, who can assess risk based on ethnicity, personal and family history and discuss appropriate testing options. A genetic counselor can be found at the National Society of Genetic Counselors website or through companies like mine, AccessDNA. Best wishes to you and your family.
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