All My Hep B Results HV DNA , LFT Advice please

[rockla]

Test Principle : Real Time PCR

Target Selected : Highly conserved pre-Core/Core region of the HBV genome across A-G genotypes is selected for amplification & detection.
Equipment : COBAS AmpliPrep and COBAS TaqMan

HBV - Hepatitis B Viral load (Quantitative) 35,935 IU/mL
Log Value                                               4.56


Test Details:
Limit of Detection: 20 IU/ml
Measuring Range: 20 - 170000000 IU/ml
Conversion Factor: 1 IU/ml - 5.82 copies/ml

Antigen Results

HBeAg-Hepatitis B Envelope Antigen
(Serum,CMIA)                          NON REACTIVE(0.41) S/CO Non Reactive: = 1.0
Anti HBe-Ab to Hepatitis B Envelope Ag
(Serum,CMIA)   REACTIVE(0.25) Ratio Non Reactive: > 1  Reactive:  250.00) IU/mL Non Reactive:  250.00) IU/mL Non Reactive: < 0.05

Can you advise how does it looks overall ? I would be going to hepatologist to give further advice as my partner wanted to clear the doubts before marriage.

[stef2011]

HBsAg Screening
(Serum,CLIA) REACTIVE(> 250.00) IU/mL Non Reactive:  250.00) IU/mL Non Reactive: < 0.05

this is wrong, they must dilute the sample to make hbsag quantity or use the new automated kits

blood samples are not useful to know if liver is ok, you can have cirrhosis and all blood tests normal

[rockla]

So what test would you recommend ?

And please tell me is the Viral Load Result too high/high/moderate ?

My liver sonography was also all good

[rockla]

And well you are scaring me :-) :-) ;-)

Lets just be positive about things if things are going to happen it will happen.

BTW I'm 31

[Royal36]

I think the best test is Fibroscan if n't you have to go for the biopsy i guess.

[stef2011]

My liver sonography was also all good

ultrasound cannot see cirrhosis, fibrosis or liver damage.if you see a damaged liver on US your liver is so advanced cirrhosis to be end stage with nothing to do.also blood tests may see a cirrhosis but like for US when all blood tests are absnormal liver is so damaged to be on end stage with very little possibilities
US is just to detect liver cancer or fatty liver

only fibroscan see a healthy liver and all levels of fibrosis before cirrhosis and then all stages of seveirty within cirrhosis

hbvdna has little meaning as regards liver damage and also little meaning without all other tests.if undetectable for many years liver is probably not damaged but only fibroscan will tell for sure

[stef2011]

you need hbsag to tell if you can easily clear infection by immune modulators like peginterferon, hbvdna can be made und by antivirals anyway but that doesn t mean clearing the infection but just stopping liver damage