Need interpretation of Hepatitis B medical test results

[Arifur]

Hi,

I was diagnosed with hepatitis B few years ago and couldn't take vaccination because doctor said: "Unless your condition is BETTER and STEADY, you should not take vaccine."

Very recently I have got my medical test results for Hepatitis B. The recent test results are given below. I would really appreciate if any professional could interpret the results for me.

1. ALT (SGPT) = 15.90 U/L [Given reference value on the result for men: 0.01-41.0 U/L]

2. HBeAg = Non-Reactive (S/CO: 0.297) [Given reference value on the result: Non-Reactive is =1.0]

3. HBV DNA Viral Load (PCR tech. , CFX 96 instrument, Altona HBV PCR Kit reagent) = 332 IU/ml [Result shows Viremia]. Back in 2010, HBV DNA Viral Load showed: "Virus not detected."

Please provide your valuable comments and opinions on these test results. I am really worried.

Thank you.

[sorte]

what is sensitivity of modern assays ?

[KumarGre]

Please trust results from Roche or Abbott kits as these US-FDA approved kits for HBV viral load monitoring. Altono is not certified one, so there is a always a risk of poor test performance.

Regards.
Dr. Kumar

[StephenCastlecrag]

Back in 2010, the PCR assay to measure your hbvdna is less sensitive, so "not detected" most likely means less than 500 iu/ml. So your new hbvdna result is consistent with your old one. Your ALT is normal, HBeAg negative, low viral load, so I think you are still in the inactive (low replicative) phase. Just keep at least a yearly checkup.
Vaccination against HBV is useless if you were already infected.