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My lymphocytes and hbv

I've made some lymphocytes tests, any comments in the context of hbv appreciated:

Leukocytes 6,07 ×103/μl [4,40 - 11,30]
% lymph 43,3 % [21,8 - 53,1]
Lymphocytes 2628 cell/μl
% CD3+ (lymph T) 76,7 % [59,7 - 82,0]
CD3+ (lymph T) 2016 cell/μl [900 - 2600]
% CD3+CD4+ (helper lymph) 52,4 % [30,4 — 51,2] H
CD3+CD4+ (helper lymph) 1378 cell/μl [500 - 1600]
% CD3+CD8+ (cytotoxic lymph) 22,4 % [19,0 - 38,9]
CD3+CD8+ (cytotoxic lymph) 589 cell/μl [300 - 1200]
CD4/CD8 2,3 [0,8 - 2,5]

I'm not on any therapy yet, starting peginf soon. Viral load fluctuated from 5600 to 650 this year. I use supplements like d3, magnesium, k2mk7. Gonna have more tests like IL-2, IL-6, IL-10, TNF-alpha in 2-3 weeks.
Best Answer
Avatar universal
should I start medication with pegintf??

yes

how much Time it will take to clear the virus??

1-2 years on peg, it is not possible to predict the time you will lose it, it can be in the 2 years treatment or in the following 5 years, peg keeps working even after you have finished when you have response
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Avatar universal
seems that I found some answer for the second question http://www.ijidonline.com/article/S1201-9712%2812%2901248-9/abstract
Helpful - 0
Avatar universal
Got one question, not related to topic. We know that hbv dna integrates into different parts of the body, tissues, not necessary only the liver. I heard about genome integration etc ..
Is it cleaned after successful seroconversion not matter spontaneous or induced by drugs ? As I know there may stay a bit in the liver as cccdna how about other parts of the body.
Another question, if HBV infected man can pass it to the infant during insemination ? As I guess there may be some hbv dna in sperm.
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Avatar universal
sorry for for stupid question..should I start medication with pegintf?? how much Time it will take to clear the virus??
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Avatar universal
seems that it's required to clean any infected cells, so maybe its normal to have it higher on chronic hbv

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103008
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Avatar universal
a noninflamed person would have a tnfalpha of 1 to 2 pg/ml. But inflammatory conditions are quite common. i do not remember  the typical hbv profile for this cytokine.
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Avatar universal
no problems, all good for max pegintf response

genotype A and B easier response, D and C worst
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