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Viread to treat severe acute Hep B

Hi and thanks for looking at this post. I have been diagnosed with Hep B. I was admitted to hospital with exceptional readings (ALT >4,000, bilirubin 180, all pho 162, gamma get 417, AST >2,500). I've been given various drips and the numbers are coming down. ALT has now halved. In addition to the drips I was also put on Viread.
My physician was concerned how my immune system was attacking the liver and between all treatments, in three days the readings are coming down. My jaundice is going and my urine now looking paler (almost normal).
Given the symptoms indicate a severe acute response to infection, does this suggest my body will put up a good fight to rid itself of the virus. Also, is there a risk Viread could actually lead to my body not developing the antibodies? I've read the following study, which suggests Viread can be highly effective in treating severe acute Hep B and also assist (or at least not inhibit) the development of antibodies.
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2008-1079678
I'm a 32 year old male and believe I acquired Hep B four months before symptoms began.
Thanks for any advice or observations!
3 Responses
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Avatar universal
Its a small number of chronically infected patients that svr.

But your ALT is very very high so maybe your doc is playing it safe?
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Avatar universal
Did Nigel McGuiness use steroids whilst he was wrestling? Maybe that weakened his immune system?

Hence viread helped
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Avatar universal
acute hbv clear itself in adults
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4 Comments
I thought it was in ~90% of cases but fear Virean during the acute phase could lead to antibodies not forming if the immune system determines the virus is in retreat or being eliminated. Thanks
Stef, I know a wrestler.. his name is Nigel McGuiness (also know as Desmond Wolfe), who got Hep B back in 2011. His body did not clear Hep B in the acute stage.

The doctor's put him on Viread and  he cleared and developed anti-bodies with the help of this medication. I understand that the body is supposed to clear itself of this virus, but sometimes the doctor's may see something different and opt to treat it a little different. I've been chatting with him to see if he had any tips as to how he helped along with clearing of the virus. So far, what I got out of him, was that he did not take any supplements and just the medication alone.

So yes, there is a chance for someone to go on Viread, even with an acute stage virus.
Thanks luckyman, that is reassuring.
My physician has just told me that only a tiny number of people who contract Hep B go on to successful seroconversion. From what I've read though, more than 90% of adults seroconvert by the end of the acute stage. He said he can't yet be certain whether I am still in the acute stage, even though all the severe symptoms point to it being acute (as well as the suspected date of infection). This really worries me that I've been put on Viread too soon and the body's immune system might not naturally rid the virus.
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