what do you mean by off the label drug alinia? can i buy it over the counter or i need to have a prescription first?im sorry stef i just dont have knowledge when it comes to new treatments. im from philipines.is it possible that we have that drug here in our country.
thanks for the infos. i hope your doing well.
yes you can just monitor and start therapy in case you detect liver damage by fibroscan higer/equal to f2 because now your immune system is already doing what curent approved drugs do
as i said earlier you might try alinia which is off label and has no sides and eradicates hbsag in the highest percentage compared to any hbv drug
i have had your condition most of my life so i made no therapy and monitored every 6/12 months as doctors said, this was wrong because i ended with cirrhosis at 40yo even with low alt, low hbvdna.
my sister had same condition as me but higher hbvdna so she tried interferon and now at least she has no cirrhosis
you must monitor closely every 3 months alt, hbvdna and every 6 month ultrasound and fibroscan.
Alt must be lower than 30 because alt at 30-40 can still make cirroshis (even if very low rate but you never know..i was in that very low rate for example)
You do not treatment now. Just monitor yearly for viral load.
im only 23 yrs old having that 1000iu/ml of hbv dna. positive hbsag and negative hbeag,
all other markers negative. does this mean i dont need to undergo any treatment?just monitoring ang right diet?tnx
antivirals except alinia and interferon have resistance issues that might make disease much worst if you are young and must use them for life
so the risk of resistance is high in your case and cure almost zero in your case hbvdna 1000iu/ml usually have normal alt and no liver damage.infact no to update good doctor will start you on antivirals, they will probably say just monitor
also consider etv and tdf do not clear hbsag so they don't cure hbv, they just lower hbvdna when it is high and stop liver damage but in your case hbvdna and alt are already close to normal
in your case only interferon, alinia are choices that can make any good by making hbsag negative, there are no other known therapies available to do this
what if im hbeag negative and my hbvdna is 1000iu/ml. it is less than 2000iu/ml right? so i do have a chance to decrease it more or even clear it by antivirals?tnx
Well, eAg+ve/eAb-ve treatment ends with e-Sero conversion. However eAg-ve/eAb+ve has no treatment endpoint (until s-Sero conversion).
Some patients start quickly with eAg-ve, but will have active liver disease.
Best thing is to get viral load checked regularly and ensure it is <2000 IU/ml for eAg -ve patients.
Yes, my understanding is that if your e antigen is negative, you are less contagious. Do more research. I am not an expert.