Thanks stef, for shedding some light on this.
http://www.hivandhepatitis.com/hepatitis-b/hepatitis-b-topics/hbv-treatment/4073-easl-2013-truvada-works-best-for-immune-tolerant-hepatitis-b-patients-but-do-they-need-treatment
these are the comments from easl where study was presented but first of all do immune tollerant patients need treatment?
no, not this type of treatment because hbvdna makes no damage for them while truvada makes a lot of damage since they are young and they sum truvada toxicity on kidneys and mitocondrial toxicity without any effect on the virus
Hi stef,
Here is conclusion from this study
"In HBeAg-positive patients with chronic HBV infection, high viral loads, normal levels of ALT, and therapy with the combination of TDF and emtricitabine provided better viral suppression than TDF alone, although rates of HBeAg seroconversion and HBsAg loss were low."
yes but what about conclusions of this study which i see not reported here?it was a failure in the conclusions report, none developed any immunity so relapsed stopping truvada which cant be obviously taken for life, treatment during immune tollerant phase by truvada is a failure