Not sure for what reasons but seems like at this point Replicor isn't really attracting big companies. Maybe it's because of the cost of the med, maybe they don't have enough data or maybe their even a fraud company (certainly hope not).
But trust me if Replicor works, big pharmas would be in LINE to buy them out. In a few years patents are expiring so whoever wants the $1 Billion per year market share for Hep B, they have an easy opportunity.
Seriously will all the patents expiring, the money is in curing patients with Hep B. also the market for people who would be willing to try a cure is WAY bigger than people willing to go on antivirals.
GS 9620 I wanted to try and was on the list of to be participants last year. Waited six months. Then they forgot about me. Then I was told only TDF takers were included. Things they say on the phone differs somewhat to what is in fine print.
Everything is very impersonal at how these companies look at us and the medical staff that does these trials. That is how I feel based on my experience. Yet there is a rule and a law that makes all this acceptable medical practice.
Nobody is really after hbv cure. If they were Replicor stuff would be already integrated into therapy. working out the details how long to keep person on interferon or zadaxin can be worked out as they go about treating people.
They say that there are doctors out there that are not afraid of regulations that have access to new agents. If this is the case we all like to hear from you.
I meant that it is good that this substance stimulates interferon. For us whatever new they try is a good news anyway. Our own body interferon may be more effective then synthetic they give us. And may do less damage to the body so revovery after treatment will be faster.
Of course they could move faster with this. They give higher doses to cancer patients already. So why not just based on their doses give us the same amount of imiquimod? After all with nucs they give us doses that were developed for HIV.
As for side effects we should not worry to much about. The damage that hbv causes slowly is the major side effect that ruins life and its experience. We are not really living with this you know.
So as far as me I am ready to try anything provided I believe in this.
Correction: far from good news*
Did you read the dosing in there. It's far dorm good news. 2mg/kg. it would be at least over 100mg per person, and in the human study 12mg was the highest they gave which had similar sides as interferon.
This is also great news. Now the way I see it. Why not begin to give this medicine to those that want to try it. And follow people. Say somebody takes it 6 -12 months. 1000 or more people take it and report their results. They could just mail that stuff out to people. It is cheap. http://www.alibaba.com/trade/search?fsb=y&IndexArea=product_en&CatId=&SearchText=imiquimod