Aa
Incivek duration?
Has anybody stayed on Incivek longer than 12 weeks? If so, what were results?
I am Geno Type 1a Hep C foe 30 yrs. VL 11.4 at start of treatment. VL 470 @ 27 days after first shot.
Little sx so far. Tired, shortness of breath, slight rash. All manageble so far.
I am Geno Type 1a Hep C foe 30 yrs. VL 11.4 at start of treatment. VL 470 @ 27 days after first shot.
Little sx so far. Tired, shortness of breath, slight rash. All manageble so far.
Best Answer
You are only beginning this treatment. I predict that by the time you get to week 10 you will no longer even consider taking the Incivek longer than 12 weeks. Besides, the risk of adverse events increases dramatically beyond 12 weeks. The rash can get really really nasty and if it gets systemic, which happened a lot more often past 12 weeks, you could end up with SJS or DRESS and you DO not want to go there! Please discard this idea now!
Looking for someone who has info on people treated longer than 12 weeks on Incivek is my ? thanks
There is no benefit whatsover with incresed risk of adverse events
Best.
Will
Final PROVE 3 SVR Results Arm 1:
12 weeks of telaprevir, Peg-IFN & RBV, followed by 12 weeks of only peg-IFN & RBV*
Arm 2:
24 weeks of telaprevir, Peg-IFN & RBV, followed by 24 weeks of only peg-IFN & RBV*
Arm 3:
24 weeks of telaprevir & Peg-IFN (no ribavirin)*
Arm 4:
48-week Control Arm of Peg-IFN & RBV*
Prior Nonresponse1 39% 38% 11% 9%
Prior Relapse2 69% 76% 42% 20%
Prior Breakthrough 57% 62% 36% 40%
All Patients 51% 53% 24% 14%
Read more: New England Journal of Medicine Publishes PROVE 3 Trial Showing Telaprevir-Based Regimens Significantly Increased Sustaine - FierceBiotech http://www.fiercebiotech.com/press-releases/new-england-journal-medicine-publishes-prove-3-trial-showing-telaprevir-based-regimen#ixzz1ee6hfy1X
Subscribe: http://www.fiercebiotech.com/signup?sourceform=Viral-Tynt-FierceBiotech-FierceBiotech
Best.
Will
Final PROVE 3 SVR Results Arm 1:
12 weeks of telaprevir, Peg-IFN & RBV, followed by 12 weeks of only peg-IFN & RBV*
Arm 2:
24 weeks of telaprevir, Peg-IFN & RBV, followed by 24 weeks of only peg-IFN & RBV*
Arm 3:
24 weeks of telaprevir & Peg-IFN (no ribavirin)*
Arm 4:
48-week Control Arm of Peg-IFN & RBV*
Prior Nonresponse1 39% 38% 11% 9%
Prior Relapse2 69% 76% 42% 20%
Prior Breakthrough 57% 62% 36% 40%
All Patients 51% 53% 24% 14%
Read more: New England Journal of Medicine Publishes PROVE 3 Trial Showing Telaprevir-Based Regimens Significantly Increased Sustaine - FierceBiotech http://www.fiercebiotech.com/press-releases/new-england-journal-medicine-publishes-prove-3-trial-showing-telaprevir-based-regimen#ixzz1ee6hfy1X
Subscribe: http://www.fiercebiotech.com/signup?sourceform=Viral-Tynt-FierceBiotech-FierceBiotech
If you mean a trial with naive"s that did 24 tela...no .The prove 1 and 2 were both naive"s tela 12 and then prove 3 was tx. exp. where there was a tela 24 arm...
Best ..
Will
Best ..
Will
It hasn't been tested otherwise, the results would be the same on tx experienced versus tx naives, no doctor worth their salt is going to prescribe it and your insurance won't pay for it anyway.
not on a boat, not on a goat, not on a train, not in the rain,
not in a trial or in a red sweater
24 weeks just isn't better!!
willy
not on a boat, not on a goat, not on a train, not in the rain,
not in a trial or in a red sweater
24 weeks just isn't better!!
willy
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