I'm gen 1a, I cleared the virus week 12 and then relapsed one month after tx.
I'm white and have less severe liver damage as well. These are positives during tx. With your response I would stop tx, and wait for the PI's. I know it's difficult to accept.
maybe I'll just do 48 weeks and see. If i get SVR perfect if not Telaprevir will be almost out.
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You might want to take some time and read about some members experiences with interferon before committing to a program with very little chance of success.
The fact you have little or no symptons now doesn't mean that you won't have symptons down the road, even after you stop taking the treatment drugs.
These are very powerful drugs that only make sense when the rewards outweigh the risks. You are the hardest to treat genotype -- you are not responding -- you have no liver damage -- and there are better drugs around the corner. Respect the facts and respect the stories of the people in the link below. I would stop treatment now and wait.
http://www.medhelp.org/health_pages/Hepatitis/Members-Comment-on-Side-Effects-of-the-Treatment-Drugs-During--After-Treatment-/show/530?cid=64
good points and I understand what you are saying. this disease is so hard to get a feel for and nothing is consistent. for the most part everyone reacts different.
Take care
i don`t think how you "feel" is an indicator of anything on tx
in terms of tx success.
especially with INF impacting your serotonin levels ect...
Some feel really bad in the beginning only to "level" out
later on , others start easy and get hit with a "truck" later on
it all has no meaning for SVR chances.
I sometimes get great labs feeling like s**t and not so good labs
but feeling great.
No, I am not saying that being detected at 24 weeks is reason to stay on...absolutely not. I'm saying over a 3 log drop at 8 weeks, especially when feeling ok, is reason to really give it some thought. Since the patient is feeling well, if he/she clears, it may end up worth it not to have to do a protease.
You are right about the studies showing anemia is a good indicator of response. That wasn't my point either. I think I am not explaining myself too well today. What I am saying is that a lot of people have at least a 2 por 3 point drop in hemoglobin and feel just fine. My first combo treatment, I started with a hemoglobin over 16. It dropped to around 12 and I didn't feel anything concerning. No cough, no out of breath, etc. That's all I meant. I'm really sorry I confused you.
Thanks for your patience
Study after study have shown anemia to be a positive indicator of SVR. If someones HGB doesn't have at least a 2 point drop early on then they are not getting enough Riba.
Not sure I understand, are you saying the original poster should continue tx even if they are still unde at 24 weeks?
I'm sure you are aware that someone still detectable at 24 weeks has less then 2% chance of SVR. And I don't think most doctors will continue tx or insurance will pay for tx if that is the case.
the only way tx will benefit someone that is still detectable after 12 weeks is if they have cirrhosis. Otherwise stopping is the right choice. Risk outweighs benefit in this case.